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CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy.
Rodriguez-Garcia A, Lynn RC, Poussin M, Eiva MA, Shaw LC, O'Connor RS, Minutolo NG, Casado-Medrano V, Lopez G, Matsuyama T, Powell DJ Jr. Rodriguez-Garcia A, et al. Among authors: minutolo ng. Nat Commun. 2021 Feb 9;12(1):877. doi: 10.1038/s41467-021-20893-2. Nat Commun. 2021. PMID: 33563975 Free PMC article.
T-cell target antigens across major gynecologic cancers.
Rodriguez-Garcia A, Minutolo NG, Robinson JM, Powell DJ. Rodriguez-Garcia A, et al. Among authors: minutolo ng. Gynecol Oncol. 2017 Jun;145(3):426-435. doi: 10.1016/j.ygyno.2017.03.510. Epub 2017 Apr 2. Gynecol Oncol. 2017. PMID: 28377094 Review.
Macrophage-Based Approaches for Cancer Immunotherapy.
Anderson NR, Minutolo NG, Gill S, Klichinsky M. Anderson NR, et al. Among authors: minutolo ng. Cancer Res. 2021 Mar 1;81(5):1201-1208. doi: 10.1158/0008-5472.CAN-20-2990. Epub 2020 Nov 17. Cancer Res. 2021. PMID: 33203697 Review.
Expression of inducible factors reprograms CAR-T cells for enhanced function and safety.
Smole A, Benton A, Poussin MA, Eiva MA, Mezzanotte C, Camisa B, Greco B, Sharma P, Minutolo NG, Gray F, Bear AS, Baroja ML, Cummins C, Xu C, Sanvito F, Goldgewicht AL, Blanchard T, Rodriguez-Garcia A, Klichinsky M, Bonini C, June CH, Posey AD Jr, Linette GP, Carreno BM, Casucci M, Powell DJ Jr. Smole A, et al. Among authors: minutolo ng. Cancer Cell. 2022 Dec 12;40(12):1470-1487.e7. doi: 10.1016/j.ccell.2022.11.006. Cancer Cell. 2022. PMID: 36513049 Free PMC article.