Minnikin DE - Search Results

1

The methyl-branched fortifications of Mycobacterium tuberculosis.

Minnikin DE, Kremer L, Dover LG, Besra GS. Minnikin DE, et al. Chem Biol. 2002 May;9(5):545-53. doi: 10.1016/s1074-5521(02)00142-4. Chem Biol. 2002. PMID: 12031661 Review.

2

Biphenyl-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme.

Senior SJ, Illarionov PA, Gurcha SS, Campbell IB, Schaeffer ML, Minnikin DE, Besra GS. Senior SJ, et al. Among authors: minnikin de. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3685-8. doi: 10.1016/j.bmcl.2003.08.015. Bioorg Med Chem Lett. 2003. PMID: 14552758

3

Acetylene-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme.

Senior SJ, Illarionov PA, Gurcha SS, Campbell IB, Schaeffer ML, Minnikin DE, Besra GS. Senior SJ, et al. Among authors: minnikin de. Bioorg Med Chem Lett. 2004 Jan 19;14(2):373-6. doi: 10.1016/j.bmcl.2003.10.061. Bioorg Med Chem Lett. 2004. PMID: 14698162

4

LosA, a key glycosyltransferase involved in the biosynthesis of a novel family of glycosylated acyltrehalose lipooligosaccharides from Mycobacterium marinum.

Burguière A, Hitchen PG, Dover LG, Kremer L, Ridell M, Alexander DC, Liu J, Morris HR, Minnikin DE, Dell A, Besra GS. Burguière A, et al. Among authors: minnikin de. J Biol Chem. 2005 Dec 23;280(51):42124-33. doi: 10.1074/jbc.M507500200. Epub 2005 Oct 28. J Biol Chem. 2005. PMID: 16257960 Free article.

5

Symmetrical and unsymmetrical analogues of isoxyl; active agents against Mycobacterium tuberculosis.

Bhowruth V, Brown AK, Reynolds RC, Coxon GD, Mackay SP, Minnikin DE, Besra GS. Bhowruth V, et al. Among authors: minnikin de. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4743-7. doi: 10.1016/j.bmcl.2006.06.095. Epub 2006 Jul 27. Bioorg Med Chem Lett. 2006. PMID: 16875817

6

Loss of a mycobacterial gene encoding a reductase leads to an altered cell wall containing beta-oxo-mycolic acid analogs and accumulation of ketones.

Bhatt A, Brown AK, Singh A, Minnikin DE, Besra GS. Bhatt A, et al. Among authors: minnikin de. Chem Biol. 2008 Sep 22;15(9):930-9. doi: 10.1016/j.chembiol.2008.07.007. Chem Biol. 2008. PMID: 18804030 Free PMC article.

7

Analogues of thiolactomycin: potential drugs with enhanced anti-mycobacterial activity.

Douglas JD, Senior SJ, Morehouse C, Phetsukiri B, Campbell IB, Besra GS, Minnikin DE. Douglas JD, et al. Among authors: minnikin de. Microbiology (Reading). 2002 Oct;148(Pt 10):3101-3109. doi: 10.1099/00221287-148-10-3101. Microbiology (Reading). 2002. PMID: 12368443 Free article.

8

Synthesis and properties of methyl 5-(1'R,2'S)-(2-octadecylcycloprop-1-yl)pentanoate and other omega-19 chiral cyclopropane fatty acids and esters related to mycobacterial mycolic acids.

Coxon GD, Al Dulayymi JR, Morehouse C, Brennan PJ, Besra GS, Baird MS, Minnikin DE. Coxon GD, et al. Among authors: minnikin de. Chem Phys Lipids. 2004 Jan;127(1):35-46. doi: 10.1016/j.chemphyslip.2003.09.001. Chem Phys Lipids. 2004. PMID: 14706739

9

Novel prenyl-linked benzophenone substrate analogues of mycobacterial mannosyltransferases.

Guy MR, Illarionov PA, Gurcha SS, Dover LG, Gibson KJ, Smith PW, Minnikin DE, Besra GS. Guy MR, et al. Among authors: minnikin de. Biochem J. 2004 Sep 15;382(Pt 3):905-12. doi: 10.1042/BJ20040911. Biochem J. 2004. PMID: 15202931 Free PMC article.

10

A mycolic acid-specific CD1-restricted T cell population contributes to acute and memory immune responses in human tuberculosis infection.

Montamat-Sicotte DJ, Millington KA, Willcox CR, Hingley-Wilson S, Hackforth S, Innes J, Kon OM, Lammas DA, Minnikin DE, Besra GS, Willcox BE, Lalvani A. Montamat-Sicotte DJ, et al. Among authors: minnikin de. J Clin Invest. 2011 Jun;121(6):2493-503. doi: 10.1172/JCI46216. Epub 2011 May 16. J Clin Invest. 2011. PMID: 21576820 Free PMC article.

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