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ORF3c is expressed in SARS-CoV-2-infected cells and inhibits innate sensing by targeting MAVS.
Müller M, Herrmann A, Fujita S, Uriu K, Kruth C, Strange A, Kolberg JE, Schneider M, Ito J, Müller MA, Drosten C, Ensser A; Genotype to Phenotype Japan (G2P-Japan) Consortium; Sato K, Sauter D. Müller M, et al. EMBO Rep. 2023 Dec 6;24(12):e57137. doi: 10.15252/embr.202357137. Epub 2023 Oct 23. EMBO Rep. 2023. PMID: 37870297 Free PMC article.
Independent loss events of a functional tetherin gene in galliform birds.
Krchlíková V, Lotke R, Haußmann I, Reinišová M, Kučerová D, Pecnová Ľ, Ungrová L, Hejnar J, Sauter D, Elleder D. Krchlíková V, et al. J Virol. 2023 Oct 31;97(10):e0080323. doi: 10.1128/jvi.00803-23. Epub 2023 Sep 15. J Virol. 2023. PMID: 37712707 Free PMC article.
Carrageenan-containing over-the-counter nasal and oral sprays inhibit SARS-CoV-2 infection of airway epithelial cultures.
Schütz D, Conzelmann C, Fois G, Groß R, Weil T, Wettstein L, Stenger S, Zelikin A, Hoffmann TK, Frick M, Müller JA, Münch J. Schütz D, et al. Am J Physiol Lung Cell Mol Physiol. 2021 May 1;320(5):L750-L756. doi: 10.1152/ajplung.00552.2020. Epub 2021 Feb 9. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33561380 Free PMC article.