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Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease.
Alysandratos KD, Russo SJ, Petcherski A, Taddeo EP, Acín-Pérez R, Villacorta-Martin C, Jean JC, Mulugeta S, Rodriguez LR, Blum BC, Hekman RM, Hix OT, Minakin K, Vedaie M, Kook S, Tilston-Lunel AM, Varelas X, Wambach JA, Cole FS, Hamvas A, Young LR, Liesa M, Emili A, Guttentag SH, Shirihai OS, Beers MF, Kotton DN. Alysandratos KD, et al. Among authors: minakin k. Cell Rep. 2021 Aug 31;36(9):109636. doi: 10.1016/j.celrep.2021.109636. Cell Rep. 2021. PMID: 34469722 Free PMC article.
Generation of human alveolar epithelial type I cells from pluripotent stem cells.
Burgess CL, Huang J, Bawa PS, Alysandratos KD, Minakin K, Ayers LJ, Morley MP, Babu A, Villacorta-Martin C, Yampolskaya M, Hinds A, Thapa BR, Wang F, Matschulat A, Mehta P, Morrisey EE, Varelas X, Kotton DN. Burgess CL, et al. Among authors: minakin k. Cell Stem Cell. 2024 May 2;31(5):657-675.e8. doi: 10.1016/j.stem.2024.03.017. Epub 2024 Apr 19. Cell Stem Cell. 2024. PMID: 38642558 Free article.
Impaired AMPK Control of Alveolar Epithelial Cell Metabolism Promotes Pulmonary Fibrosis.
Rodriguez LR, Alysandratos KD, Katzen J, Murthy A, Barboza WR, Tomer Y, Acin-Perez R, Petcherski A, Minakin K, Carson P, Iyer S, Chavez K, Cooper CH, Babu A, Weiner AI, Vaughan AE, Arany Z, Shirihai OS, Kotton DN, Beers MF. Rodriguez LR, et al. Among authors: minakin k. bioRxiv [Preprint]. 2024 Mar 28:2024.03.26.586649. doi: 10.1101/2024.03.26.586649. bioRxiv. 2024. PMID: 38585863 Free PMC article. Preprint.
Generation of human alveolar epithelial type I cells from pluripotent stem cells.
Burgess CL, Huang J, Bawa P, Alysandratos KD, Minakin K, Morley MP, Babu A, Villacorta-Martin C, Hinds A, Thapa BR, Wang F, Matschulat AM, Morrisey EE, Varelas X, Kotton DN. Burgess CL, et al. Among authors: minakin k. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524655. doi: 10.1101/2023.01.19.524655. bioRxiv. 2023. PMID: 36711505 Free PMC article. Updated. Preprint.
Culture impact on the transcriptomic programs of primary and iPSC-derived human alveolar type 2 cells.
Alysandratos KD, Garcia-de-Alba C, Yao C, Pessina P, Huang J, Villacorta-Martin C, Hix OT, Minakin K, Burgess CL, Bawa P, Murthy A, Konda B, Beers MF, Stripp BR, Kim CF, Kotton DN. Alysandratos KD, et al. Among authors: minakin k. JCI Insight. 2023 Jan 10;8(1):e158937. doi: 10.1172/jci.insight.158937. JCI Insight. 2023. PMID: 36454643 Free PMC article.