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PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis.
Araya J, Tsubouchi K, Sato N, Ito S, Minagawa S, Hara H, Hosaka Y, Ichikawa A, Saito N, Kadota T, Yoshida M, Fujita Y, Utsumi H, Kobayashi K, Yanagisawa H, Hashimoto M, Wakui H, Ishikawa T, Numata T, Kaneko Y, Asano H, Yamashita M, Odaka M, Morikawa T, Nishimura SL, Nakayama K, Kuwano K. Araya J, et al. Among authors: minagawa s. Autophagy. 2019 Mar;15(3):510-526. doi: 10.1080/15548627.2018.1532259. Epub 2018 Oct 13. Autophagy. 2019. PMID: 30290714 Free PMC article.
Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells.
Minagawa S, Araya J, Numata T, Nojiri S, Hara H, Yumino Y, Kawaishi M, Odaka M, Morikawa T, Nishimura SL, Nakayama K, Kuwano K. Minagawa S, et al. Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L391-401. doi: 10.1152/ajplung.00097.2010. Epub 2010 Dec 17. Am J Physiol Lung Cell Mol Physiol. 2011. PMID: 21224216 Free PMC article.
Insulin-dependent phosphatidylinositol 3-kinase/Akt and ERK signaling pathways inhibit TLR3-mediated human bronchial epithelial cell apoptosis.
Numata T, Araya J, Fujii S, Hara H, Takasaka N, Kojima J, Minagawa S, Yumino Y, Kawaishi M, Hirano J, Odaka M, Morikawa T, Nishimura SL, Nakayama K, Kuwano K. Numata T, et al. Among authors: minagawa s. J Immunol. 2011 Jul 1;187(1):510-9. doi: 10.4049/jimmunol.1004218. Epub 2011 Jun 6. J Immunol. 2011. PMID: 21646299
Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β.
Kitamura H, Cambier S, Somanath S, Barker T, Minagawa S, Markovics J, Goodsell A, Publicover J, Reichardt L, Jablons D, Wolters P, Hill A, Marks JD, Lou J, Pittet JF, Gauldie J, Baron JL, Nishimura SL. Kitamura H, et al. Among authors: minagawa s. J Clin Invest. 2011 Jul;121(7):2863-75. doi: 10.1172/JCI45589. Epub 2011 Jun 6. J Clin Invest. 2011. PMID: 21646718 Free PMC article.
Autophagy induction by SIRT6 through attenuation of insulin-like growth factor signaling is involved in the regulation of human bronchial epithelial cell senescence.
Takasaka N, Araya J, Hara H, Ito S, Kobayashi K, Kurita Y, Wakui H, Yoshii Y, Yumino Y, Fujii S, Minagawa S, Tsurushige C, Kojima J, Numata T, Shimizu K, Kawaishi M, Kaneko Y, Kamiya N, Hirano J, Odaka M, Morikawa T, Nishimura SL, Nakayama K, Kuwano K. Takasaka N, et al. Among authors: minagawa s. J Immunol. 2014 Feb 1;192(3):958-68. doi: 10.4049/jimmunol.1302341. Epub 2013 Dec 23. J Immunol. 2014. PMID: 24367027
Selective targeting of TGF-β activation to treat fibroinflammatory airway disease.
Minagawa S, Lou J, Seed RI, Cormier A, Wu S, Cheng Y, Murray L, Tsui P, Connor J, Herbst R, Govaerts C, Barker T, Cambier S, Yanagisawa H, Goodsell A, Hashimoto M, Brand OJ, Cheng R, Ma R, McKnelly KJ, Wen W, Hill A, Jablons D, Wolters P, Kitamura H, Araya J, Barczak AJ, Erle DJ, Reichardt LF, Marks JD, Baron JL, Nishimura SL. Minagawa S, et al. Sci Transl Med. 2014 Jun 18;6(241):241ra79. doi: 10.1126/scitranslmed.3008074. Sci Transl Med. 2014. PMID: 24944194 Free PMC article.
PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis.
Ito S, Araya J, Kurita Y, Kobayashi K, Takasaka N, Yoshida M, Hara H, Minagawa S, Wakui H, Fujii S, Kojima J, Shimizu K, Numata T, Kawaishi M, Odaka M, Morikawa T, Harada T, Nishimura SL, Kaneko Y, Nakayama K, Kuwano K. Ito S, et al. Among authors: minagawa s. Autophagy. 2015;11(3):547-59. doi: 10.1080/15548627.2015.1017190. Autophagy. 2015. PMID: 25714760 Free PMC article.
TGF-β-Dependent Dendritic Cell Chemokinesis in Murine Models of Airway Disease.
Hashimoto M, Yanagisawa H, Minagawa S, Sen D, Ma R, Murray LA, Tsui P, Lou J, Marks JD, Baron JL, Krummel MF, Nishimura SL. Hashimoto M, et al. Among authors: minagawa s. J Immunol. 2015 Aug 1;195(3):1182-90. doi: 10.4049/jimmunol.1500348. Epub 2015 Jun 24. J Immunol. 2015. PMID: 26109638 Free PMC article.
150 results