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Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys.
Nagai Y, Miyakawa N, Takuwa H, Hori Y, Oyama K, Ji B, Takahashi M, Huang XP, Slocum ST, DiBerto JF, Xiong Y, Urushihata T, Hirabayashi T, Fujimoto A, Mimura K, English JG, Liu J, Inoue KI, Kumata K, Seki C, Ono M, Shimojo M, Zhang MR, Tomita Y, Nakahara J, Suhara T, Takada M, Higuchi M, Jin J, Roth BL, Minamimoto T. Nagai Y, et al. Among authors: mimura k. Nat Neurosci. 2020 Sep;23(9):1157-1167. doi: 10.1038/s41593-020-0661-3. Epub 2020 Jul 6. Nat Neurosci. 2020. PMID: 32632286
Chemogenetic Disconnection between the Orbitofrontal Cortex and the Rostromedial Caudate Nucleus Disrupts Motivational Control of Goal-Directed Action.
Oyama K, Hori Y, Mimura K, Nagai Y, Eldridge MAG, Saunders RC, Miyakawa N, Hirabayashi T, Hori Y, Inoue KI, Suhara T, Takada M, Higuchi M, Richmond BJ, Minamimoto T. Oyama K, et al. Among authors: mimura k. J Neurosci. 2022 Aug 10;42(32):6267-6275. doi: 10.1523/JNEUROSCI.0229-22.2022. Epub 2022 Jul 6. J Neurosci. 2022. PMID: 35794012 Free PMC article.
A genetically targeted reporter for PET imaging of deep neuronal circuits in mammalian brains.
Shimojo M, Ono M, Takuwa H, Mimura K, Nagai Y, Fujinaga M, Kikuchi T, Okada M, Seki C, Tokunaga M, Maeda J, Takado Y, Takahashi M, Minamihisamatsu T, Zhang MR, Tomita Y, Suzuki N, Maximov A, Suhara T, Minamimoto T, Sahara N, Higuchi M. Shimojo M, et al. Among authors: mimura k. EMBO J. 2021 Nov 15;40(22):e107757. doi: 10.15252/embj.2021107757. Epub 2021 Oct 12. EMBO J. 2021. PMID: 34636430 Free PMC article.
563 results