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A partial agonist of PPARγ prevents paclitaxel-induced peripheral neuropathy in mice, by inhibiting neuroinflammation.
Benvenutti L, Wolff FR, Corrêa TP, Melato J, Goldoni FC, De Faveri R, Patel YBK, de Souza JA, Grockoski HA, Nilz PM, Bombardelli CL, Remor AP, Varela KG, Costa NTC, Hernandes MZ, Lacerda MG, Rodrigues KD, Milton FA, Neves FAR, Pereira MES, Kormann Imianowsky EC, de Campos Buzzi F, Brunaldi Marutani VH, Stoeberl LC, Correa R, Eller S, de Oliveira TF, Gonçalves TBP, da Silva RC, Passos GF, da Costa R, Santin JR, Quintão NLM. Benvenutti L, et al. Among authors: milton fa. Br J Pharmacol. 2024 Apr;181(7):1128-1149. doi: 10.1111/bph.16244. Epub 2023 Dec 1. Br J Pharmacol. 2024. PMID: 37721089
Chemical synthesis, docking studies and biological effects of a pan peroxisome proliferator-activated receptor agonist and cyclooxygenase inhibitor.
Santin JR, Uchôa FD, Lima Mdo C, Rabello MM, Machado ID, Hernandes MZ, Amato AA, Milton FA, Webb P, Neves Fde A, Galdino SL, Pitta IR, Farsky SH. Santin JR, et al. Among authors: milton fa. Eur J Pharm Sci. 2013 Mar 12;48(4-5):689-97. doi: 10.1016/j.ejps.2012.12.029. Epub 2013 Jan 7. Eur J Pharm Sci. 2013. PMID: 23305993
In vitro effects of European and Latin-American medicinal plants in CYP3A4 gene expression, glutathione levels, and P-glycoprotein activity.
Mazzari ALDA, Lacerda MG, Milton FA, Mulin Montechiari Machado JA, Sinoti SBP, Toullec AS, Rodrigues PM, Neves FAR, Simeoni LA, Silveira D, Prieto JM. Mazzari ALDA, et al. Among authors: milton fa. Front Pharmacol. 2022 Oct 5;13:826395. doi: 10.3389/fphar.2022.826395. eCollection 2022. Front Pharmacol. 2022. PMID: 36278236 Free PMC article.
Evaluation of the anti-inflammatory potential of Solidago microglossa (Arnica-brasileira) in vivo and its effects on PPARγ activity.
Vogas RS, Pereira MTM, Duarte LS, Carneiro MJ, Farsura AF, Machado JAMM, Costa IF, TomÉ MRN, Milton FA, Neves FAR, Andreo MA, Lopez BG, Sawaya ACHF, Pascoal VDB, Pascoal ACRF. Vogas RS, et al. Among authors: milton fa. An Acad Bras Cienc. 2020;92(2):e20191201. doi: 10.1590/0001-3765202020191201. Epub 2020 Aug 12. An Acad Bras Cienc. 2020. PMID: 32813866 Free article.
13 results