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Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations.
Fomin A, Gärtner A, Cyganek L, Tiburcy M, Tuleta I, Wellers L, Folsche L, Hobbach AJ, von Frieling-Salewsky M, Unger A, Hucke A, Koser F, Kassner A, Sielemann K, Streckfuß-Bömeke K, Hasenfuss G, Goedel A, Laugwitz KL, Moretti A, Gummert JF, Dos Remedios CG, Reinecke H, Knöll R, van Heesch S, Hubner N, Zimmermann WH, Milting H, Linke WA. Fomin A, et al. Among authors: milting h. Sci Transl Med. 2021 Nov 3;13(618):eabd3079. doi: 10.1126/scitranslmed.abd3079. Epub 2021 Nov 3. Sci Transl Med. 2021. PMID: 34731013
The structural examination of myocardial samples from patients with end-stage heart failure supported by ventricular assist devices using electron microscopy and amino acid analysis reveals low degree of reverse remodeling.
Milting H, Jacob M, Kassner A, Heimann P, Mannherz HG, Becker G, Meyer HE, Böthig D, Arusoglu L, Morshuis M, Körfer R, El Banayosy A. Milting H, et al. J Heart Lung Transplant. 2004 Apr;23(4):396-404. doi: 10.1016/S1053-2498(03)00205-5. J Heart Lung Transplant. 2004. PMID: 15063398
Influence of ACE-inhibition and mechanical unloading on the regulation of extracellular matrix proteins in the myocardium of heart transplantation candidates bridged by ventricular assist devices.
Milting H, Kassner A, Arusoglu L, Meyer HE, Morshuis M, Brendel R, Klauke B, El Banayosy A, Körfer R. Milting H, et al. Eur J Heart Fail. 2006 May;8(3):278-83. doi: 10.1016/j.ejheart.2005.09.008. Epub 2005 Nov 23. Eur J Heart Fail. 2006. PMID: 16309954 Free article.
Relevance of brain natriuretic peptide in preload-dependent regulation of cardiac sarcoplasmic reticulum Ca2+ ATPase expression.
Kögler H, Schott P, Toischer K, Milting H, Van PN, Kohlhaas M, Grebe C, Kassner A, Domeier E, Teucher N, Seidler T, Knöll R, Maier LS, El-Banayosy A, Körfer R, Hasenfuss G. Kögler H, et al. Among authors: milting h. Circulation. 2006 Jun 13;113(23):2724-32. doi: 10.1161/CIRCULATIONAHA.105.608828. Epub 2006 Jun 5. Circulation. 2006. PMID: 16754798
Selective upregulation of beta1-adrenergic receptors and dephosphorylation of troponin I in end-stage heart failure patients supported by ventricular assist devices.
Milting H, Scholz C, Arusoglu L, Freitag M, Cebulla R, Jaquet K, Körfer R, V Lewinski D, Kassner A, Brodde OE, Kögler H, El Banayosy A, Pieske B. Milting H, et al. J Mol Cell Cardiol. 2006 Sep;41(3):441-50. doi: 10.1016/j.yjmcc.2006.04.010. Epub 2006 Jun 12. J Mol Cell Cardiol. 2006. PMID: 16765375
Global gene expression analysis in nonfailing and failing myocardium pre- and postpulsatile and nonpulsatile ventricular assist device support.
Schwientek P, Ellinghaus P, Steppan S, D'Urso D, Seewald M, Kassner A, Cebulla R, Schulte-Eistrup S, Morshuis M, Röfe D, El Banayosy A, Körfer R, Milting H. Schwientek P, et al. Among authors: milting h. Physiol Genomics. 2010 Aug;42(3):397-405. doi: 10.1152/physiolgenomics.00030.2010. Epub 2010 May 11. Physiol Genomics. 2010. PMID: 20460602
Regulation of cyclic adenosine monophosphate release by selective β2-adrenergic receptor stimulation in human terminal failing myocardium before and after ventricular assist device support.
Kassner A, Toischer K, Bohms B, Kolkhof P, Abraham G, Hasenfuβ G, Morshuis M, Schulte Eistrup S, El-Banayosy A, Gummert J, Milting H. Kassner A, et al. Among authors: milting h. J Heart Lung Transplant. 2012 Oct;31(10):1127-35. doi: 10.1016/j.healun.2012.07.005. J Heart Lung Transplant. 2012. PMID: 22975104
154 results