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Optimization of Ligands Using Focused DNA-Encoded Libraries To Develop a Selective, Cell-Permeable CBX8 Chromodomain Inhibitor.
Wang S, Denton KE, Hobbs KF, Weaver T, McFarlane JMB, Connelly KE, Gignac MC, Milosevich N, Hof F, Paci I, Musselman CA, Dykhuizen EC, Krusemark CJ. Wang S, et al. Among authors: milosevich n. ACS Chem Biol. 2020 Jan 17;15(1):112-131. doi: 10.1021/acschembio.9b00654. Epub 2019 Dec 12. ACS Chem Biol. 2020. PMID: 31755685 Free PMC article.
Polycomb Paralog Chromodomain Inhibitors Active against Both CBX6 and CBX8*.
Milosevich N, Wilson CR, Brown TM, Alpsoy A, Wang S, Connelly KE, Sinclair KAD, Ponio FR, Hof R, Dykhuizen EC, Hof F. Milosevich N, et al. ChemMedChem. 2021 Oct 6;16(19):3027-3034. doi: 10.1002/cmdc.202100262. Epub 2021 Jul 23. ChemMedChem. 2021. PMID: 34174168 Free PMC article.
Selective Inhibition of CBX6: A Methyllysine Reader Protein in the Polycomb Family.
Milosevich N, Gignac MC, McFarlane J, Simhadri C, Horvath S, Daze KD, Croft CS, Dheri A, Quon TT, Douglas SF, Wulff JE, Paci I, Hof F. Milosevich N, et al. ACS Med Chem Lett. 2015 Dec 7;7(2):139-44. doi: 10.1021/acsmedchemlett.5b00378. eCollection 2016 Feb 11. ACS Med Chem Lett. 2015. PMID: 26985288 Free PMC article.
Cell-Based Ligand Discovery for the ENL YEATS Domain.
Asiaban JN, Milosevich N, Chen E, Bishop TR, Wang J, Zhang Y, Ackerman CJ, Hampton EN, Young TS, Hull MV, Cravatt BF, Erb MA. Asiaban JN, et al. Among authors: milosevich n. ACS Chem Biol. 2020 Apr 17;15(4):895-903. doi: 10.1021/acschembio.0c00124. Epub 2020 Mar 19. ACS Chem Biol. 2020. PMID: 32176478 Free PMC article.
13 results