Milne TA - Search Results

1

Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture.

Downes DJ, Smith AL, Karpinska MA, Velychko T, Rue-Albrecht K, Sims D, Milne TA, Davies JOJ, Oudelaar AM, Hughes JR. Downes DJ, et al. Among authors: milne ta. Nat Protoc. 2022 Feb;17(2):445-475. doi: 10.1038/s41596-021-00651-w. Epub 2022 Feb 4. Nat Protoc. 2022. PMID: 35121852 Free PMC article. Review.

2

Intragenic enhancers act as alternative promoters.

Kowalczyk MS, Hughes JR, Garrick D, Lynch MD, Sharpe JA, Sloane-Stanley JA, McGowan SJ, De Gobbi M, Hosseini M, Vernimmen D, Brown JM, Gray NE, Collavin L, Gibbons RJ, Flint J, Taylor S, Buckle VJ, Milne TA, Wood WG, Higgs DR. Kowalczyk MS, et al. Among authors: milne ta. Mol Cell. 2012 Feb 24;45(4):447-58. doi: 10.1016/j.molcel.2011.12.021. Epub 2012 Jan 19. Mol Cell. 2012. PMID: 22264824 Free article.

3

MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation.

Godfrey L, Kerry J, Thorne R, Repapi E, Davies JO, Tapia M, Ballabio E, Hughes JR, Geng H, Konopleva M, Milne TA. Godfrey L, et al. Among authors: milne ta. Exp Hematol. 2017 Mar;47:64-75. doi: 10.1016/j.exphem.2016.11.003. Epub 2016 Nov 14. Exp Hematol. 2017. PMID: 27856324 Free PMC article.

4

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.

Pasricha SR, Lim PJ, Duarte TL, Casu C, Oosterhuis D, Mleczko-Sanecka K, Suciu M, Da Silva AR, Al-Hourani K, Arezes J, McHugh K, Gooding S, Frost JN, Wray K, Santos A, Porto G, Repapi E, Gray N, Draper SJ, Ashley N, Soilleux E, Olinga P, Muckenthaler MU, Hughes JR, Rivella S, Milne TA, Armitage AE, Drakesmith H. Pasricha SR, et al. Among authors: milne ta. Nat Commun. 2017 Sep 1;8(1):403. doi: 10.1038/s41467-017-00500-z. Nat Commun. 2017. PMID: 28864822 Free PMC article.

5

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation.

Godfrey L, Crump NT, Thorne R, Lau IJ, Repapi E, Dimou D, Smith AL, Harman JR, Telenius JM, Oudelaar AM, Downes DJ, Vyas P, Hughes JR, Milne TA. Godfrey L, et al. Among authors: milne ta. Nat Commun. 2019 Jun 26;10(1):2803. doi: 10.1038/s41467-019-10844-3. Nat Commun. 2019. PMID: 31243293 Free PMC article.

6

The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes.

Hua P, Hester J, Adigbli G, Li R, Psaila B, Roy A, Bataille CJR, Wynne GM, Jackson T, Milne TA, Russell AJ, Davies J, Roberts I, Issa F, Watt SM. Hua P, et al. Among authors: milne ta. Blood. 2020 Nov 19;136(21):2410-2415. doi: 10.1182/blood.2020005357. Blood. 2020. PMID: 32599615 Free PMC article.

7

BET inhibition disrupts transcription but retains enhancer-promoter contact.

Crump NT, Ballabio E, Godfrey L, Thorne R, Repapi E, Kerry J, Tapia M, Hua P, Lagerholm C, Filippakopoulos P, Davies JOJ, Milne TA. Crump NT, et al. Among authors: milne ta. Nat Commun. 2021 Jan 11;12(1):223. doi: 10.1038/s41467-020-20400-z. Nat Commun. 2021. PMID: 33431820 Free PMC article.

8

Defining genome architecture at base-pair resolution.

Hua P, Badat M, Hanssen LLP, Hentges LD, Crump N, Downes DJ, Jeziorska DM, Oudelaar AM, Schwessinger R, Taylor S, Milne TA, Hughes JR, Higgs DR, Davies JOJ. Hua P, et al. Among authors: milne ta. Nature. 2021 Jul;595(7865):125-129. doi: 10.1038/s41586-021-03639-4. Epub 2021 Jun 9. Nature. 2021. PMID: 34108683

9

Author Correction: Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture.

Downes DJ, Smith AL, Karpinska MA, Velychko T, Rue-Albrecht K, Sims D, Milne TA, Davies JOJ, Oudelaar AM, Hughes JR. Downes DJ, et al. Among authors: milne ta. Nat Protoc. 2023 Oct;18(10):3155. doi: 10.1038/s41596-023-00860-5. Nat Protoc. 2023. PMID: 37369851 No abstract available.

10

MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.

Crump NT, Smith AL, Godfrey L, Dopico-Fernandez AM, Denny N, Harman JR, Hamley JC, Jackson NE, Chahrour C, Riva S, Rice S, Kim J, Basrur V, Fermin D, Elenitoba-Johnson K, Roeder RG, Allis CD, Roberts I, Roy A, Geng H, Davies JOJ, Milne TA. Crump NT, et al. Among authors: milne ta. Nat Commun. 2023 Aug 25;14(1):5208. doi: 10.1038/s41467-023-40981-9. Nat Commun. 2023. PMID: 37626123 Free PMC article.

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