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Single-Cell Transcriptomics Reveals a Conserved Metaplasia Program in Pancreatic Injury.
Ma Z, Lytle NK, Chen B, Jyotsana N, Novak SW, Cho CJ, Caplan L, Ben-Levy O, Neininger AC, Burnette DT, Trinh VQ, Tan MCB, Patterson EA, Arrojo E Drigo R, Giraddi RR, Ramos C, Means AL, Matsumoto I, Manor U, Mills JC, Goldenring JR, Lau KS, Wahl GM, DelGiorno KE. Ma Z, et al. Among authors: mills jc. Gastroenterology. 2022 Feb;162(2):604-620.e20. doi: 10.1053/j.gastro.2021.10.027. Epub 2021 Oct 23. Gastroenterology. 2022. PMID: 34695382 Free PMC article.
Mature chief cells are cryptic progenitors for metaplasia in the stomach.
Nam KT, Lee HJ, Sousa JF, Weis VG, O'Neal RL, Finke PE, Romero-Gallo J, Shi G, Mills JC, Peek RM Jr, Konieczny SF, Goldenring JR. Nam KT, et al. Among authors: mills jc. Gastroenterology. 2010 Dec;139(6):2028-2037.e9. doi: 10.1053/j.gastro.2010.09.005. Epub 2010 Sep 18. Gastroenterology. 2010. PMID: 20854822 Free PMC article.
Helicobacter pylori promotes the expression of Krüppel-like factor 5, a mediator of carcinogenesis, in vitro and in vivo.
Noto JM, Khizanishvili T, Chaturvedi R, Piazuelo MB, Romero-Gallo J, Delgado AG, Khurana SS, Sierra JC, Krishna US, Suarez G, Powell AE, Goldenring JR, Coffey RJ, Yang VW, Correa P, Mills JC, Wilson KT, Peek RM Jr. Noto JM, et al. Among authors: mills jc. PLoS One. 2013;8(1):e54344. doi: 10.1371/journal.pone.0054344. Epub 2013 Jan 23. PLoS One. 2013. PMID: 23372710 Free PMC article.
Maturity and age influence chief cell ability to transdifferentiate into metaplasia.
Weis VG, Petersen CP, Weis JA, Meyer AR, Choi E, Mills JC, Goldenring JR. Weis VG, et al. Among authors: mills jc. Am J Physiol Gastrointest Liver Physiol. 2017 Jan 1;312(1):G67-G76. doi: 10.1152/ajpgi.00326.2016. Epub 2016 Nov 23. Am J Physiol Gastrointest Liver Physiol. 2017. PMID: 27881402 Free PMC article.
179 results