Milligan G - Search Results

1

Development and Characterization of a Fluorescent Tracer for the Free Fatty Acid Receptor 2 (FFA2/GPR43).

Hansen AH, Sergeev E, Pandey SK, Hudson BD, Christiansen E, Milligan G, Ulven T. Hansen AH, et al. Among authors: milligan g. J Med Chem. 2017 Jul 13;60(13):5638-5645. doi: 10.1021/acs.jmedchem.7b00338. Epub 2017 Jun 16. J Med Chem. 2017. PMID: 28570808 Free article.

2

Orexin-1 receptor-cannabinoid CB1 receptor heterodimerization results in both ligand-dependent and -independent coordinated alterations of receptor localization and function.

Ellis J, Pediani JD, Canals M, Milasta S, Milligan G. Ellis J, et al. Among authors: milligan g. J Biol Chem. 2006 Dec 15;281(50):38812-24. doi: 10.1074/jbc.M602494200. Epub 2006 Oct 2. J Biol Chem. 2006. PMID: 17015451 Free article.

3

Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short chain fatty acids.

Stoddart LA, Smith NJ, Jenkins L, Brown AJ, Milligan G. Stoddart LA, et al. Among authors: milligan g. J Biol Chem. 2008 Nov 21;283(47):32913-24. doi: 10.1074/jbc.M805601200. Epub 2008 Sep 18. J Biol Chem. 2008. PMID: 18801738 Free article.

4

International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1, -2, and -3: pharmacology and pathophysiological functions.

Stoddart LA, Smith NJ, Milligan G. Stoddart LA, et al. Among authors: milligan g. Pharmacol Rev. 2008 Dec;60(4):405-17. doi: 10.1124/pr.108.00802. Epub 2008 Dec 1. Pharmacol Rev. 2008. PMID: 19047536 Review.

5

The action and mode of binding of thiazolidinedione ligands at free fatty acid receptor 1.

Smith NJ, Stoddart LA, Devine NM, Jenkins L, Milligan G. Smith NJ, et al. Among authors: milligan g. J Biol Chem. 2009 Jun 26;284(26):17527-39. doi: 10.1074/jbc.M109.012849. Epub 2009 Apr 27. J Biol Chem. 2009. PMID: 19398560 Free PMC article.

6

Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3.

Milligan G, Stoddart LA, Smith NJ. Milligan G, et al. Br J Pharmacol. 2009 Sep;158(1):146-53. doi: 10.1111/j.1476-5381.2009.00421.x. Br J Pharmacol. 2009. PMID: 19719777 Free PMC article. Review.

7

Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of β-arrestin-2 and activate Gα13.

Jenkins L, Brea J, Smith NJ, Hudson BD, Reilly G, Bryant NJ, Castro M, Loza MI, Milligan G. Jenkins L, et al. Among authors: milligan g. Biochem J. 2010 Dec 15;432(3):451-9. doi: 10.1042/BJ20101287. Biochem J. 2010. PMID: 20919992

8

Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3.

Schmidt J, Smith NJ, Christiansen E, Tikhonova IG, Grundmann M, Hudson BD, Ward RJ, Drewke C, Milligan G, Kostenis E, Ulven T. Schmidt J, et al. Among authors: milligan g. J Biol Chem. 2011 Mar 25;286(12):10628-40. doi: 10.1074/jbc.M110.210872. Epub 2011 Jan 10. J Biol Chem. 2011. PMID: 21220428 Free PMC article.

9

Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator.

Smith NJ, Ward RJ, Stoddart LA, Hudson BD, Kostenis E, Ulven T, Morris JC, Tränkle C, Tikhonova IG, Adams DR, Milligan G. Smith NJ, et al. Among authors: milligan g. Mol Pharmacol. 2011 Jul;80(1):163-73. doi: 10.1124/mol.110.070789. Epub 2011 Apr 15. Mol Pharmacol. 2011. PMID: 21498659 Free PMC article.

10

Experimental challenges to targeting poorly characterized GPCRs: uncovering the therapeutic potential for free fatty acid receptors.

Hudson BD, Smith NJ, Milligan G. Hudson BD, et al. Among authors: milligan g. Adv Pharmacol. 2011;62:175-218. doi: 10.1016/B978-0-12-385952-5.00006-3. Adv Pharmacol. 2011. PMID: 21907910 Review.

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