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Distinct tau prion strains propagate in cells and mice and define different tauopathies.
Sanders DW, Kaufman SK, DeVos SL, Sharma AM, Mirbaha H, Li A, Barker SJ, Foley AC, Thorpe JR, Serpell LC, Miller TM, Grinberg LT, Seeley WW, Diamond MI. Sanders DW, et al. Among authors: miller tm. Neuron. 2014 Jun 18;82(6):1271-88. doi: 10.1016/j.neuron.2014.04.047. Epub 2014 May 22. Neuron. 2014. PMID: 24857020 Free PMC article.
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds.
Holmes BB, DeVos SL, Kfoury N, Li M, Jacks R, Yanamandra K, Ouidja MO, Brodsky FM, Marasa J, Bagchi DP, Kotzbauer PT, Miller TM, Papy-Garcia D, Diamond MI. Holmes BB, et al. Among authors: miller tm. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):E3138-47. doi: 10.1073/pnas.1301440110. Epub 2013 Jul 29. Proc Natl Acad Sci U S A. 2013. PMID: 23898162 Free PMC article.
Antisense reduction of tau in adult mice protects against seizures.
DeVos SL, Goncharoff DK, Chen G, Kebodeaux CS, Yamada K, Stewart FR, Schuler DR, Maloney SE, Wozniak DF, Rigo F, Bennett CF, Cirrito JR, Holtzman DM, Miller TM. DeVos SL, et al. Among authors: miller tm. J Neurosci. 2013 Jul 31;33(31):12887-97. doi: 10.1523/JNEUROSCI.2107-13.2013. J Neurosci. 2013. PMID: 23904623 Free PMC article.
Increased 4R-Tau Induces Pathological Changes in a Human-Tau Mouse Model.
Schoch KM, DeVos SL, Miller RL, Chun SJ, Norrbom M, Wozniak DF, Dawson HN, Bennett CF, Rigo F, Miller TM. Schoch KM, et al. Among authors: miller tm, miller rl. Neuron. 2016 Jun 1;90(5):941-7. doi: 10.1016/j.neuron.2016.04.042. Epub 2016 May 19. Neuron. 2016. PMID: 27210553 Free PMC article.
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.
DeVos SL, Miller RL, Schoch KM, Holmes BB, Kebodeaux CS, Wegener AJ, Chen G, Shen T, Tran H, Nichols B, Zanardi TA, Kordasiewicz HB, Swayze EE, Bennett CF, Diamond MI, Miller TM. DeVos SL, et al. Among authors: miller tm, miller rl. Sci Transl Med. 2017 Jan 25;9(374):eaag0481. doi: 10.1126/scitranslmed.aag0481. Sci Transl Med. 2017. PMID: 28123067 Free PMC article.
Tau Kinetics in Neurons and the Human Central Nervous System.
Sato C, Barthélemy NR, Mawuenyega KG, Patterson BW, Gordon BA, Jockel-Balsarotti J, Sullivan M, Crisp MJ, Kasten T, Kirmess KM, Kanaan NM, Yarasheski KE, Baker-Nigh A, Benzinger TLS, Miller TM, Karch CM, Bateman RJ. Sato C, et al. Among authors: miller tm. Neuron. 2018 Mar 21;97(6):1284-1298.e7. doi: 10.1016/j.neuron.2018.02.015. Neuron. 2018. PMID: 29566794 Free PMC article.
282 results