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Design of protein-binding proteins from the target structure alone.
Cao L, Coventry B, Goreshnik I, Huang B, Sheffler W, Park JS, Jude KM, Marković I, Kadam RU, Verschueren KHG, Verstraete K, Walsh STR, Bennett N, Phal A, Yang A, Kozodoy L, DeWitt M, Picton L, Miller L, Strauch EM, DeBouver ND, Pires A, Bera AK, Halabiya S, Hammerson B, Yang W, Bernard S, Stewart L, Wilson IA, Ruohola-Baker H, Schlessinger J, Lee S, Savvides SN, Garcia KC, Baker D. Cao L, et al. Among authors: miller l. Nature. 2022 May;605(7910):551-560. doi: 10.1038/s41586-022-04654-9. Epub 2022 Mar 24. Nature. 2022. PMID: 35332283 Free PMC article.
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.
Cao L, Goreshnik I, Coventry B, Case JB, Miller L, Kozodoy L, Chen RE, Carter L, Walls AC, Park YJ, Strauch EM, Stewart L, Diamond MS, Veesler D, Baker D. Cao L, et al. Among authors: miller l. Science. 2020 Oct 23;370(6515):426-431. doi: 10.1126/science.abd9909. Epub 2020 Sep 9. Science. 2020. PMID: 32907861 Free PMC article.
Reconfigurable asymmetric protein assemblies through implicit negative design.
Sahtoe DD, Praetorius F, Courbet A, Hsia Y, Wicky BIM, Edman NI, Miller LM, Timmermans BJR, Decarreau J, Morris HM, Kang A, Bera AK, Baker D. Sahtoe DD, et al. Science. 2022 Jan 21;375(6578):eabj7662. doi: 10.1126/science.abj7662. Epub 2022 Jan 21. Science. 2022. PMID: 35050655 Free PMC article.
Transferrin receptor targeting by de novo sheet extension.
Sahtoe DD, Coscia A, Mustafaoglu N, Miller LM, Olal D, Vulovic I, Yu TY, Goreshnik I, Lin YR, Clark L, Busch F, Stewart L, Wysocki VH, Ingber DE, Abraham J, Baker D. Sahtoe DD, et al. Among authors: miller lm. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2021569118. doi: 10.1073/pnas.2021569118. Proc Natl Acad Sci U S A. 2021. PMID: 33879614 Free PMC article.
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.
Cao L, Goreshnik I, Coventry B, Case JB, Miller L, Kozodoy L, Chen RE, Carter L, Walls L, Park YJ, Stewart L, Diamond M, Veesler D, Baker D. Cao L, et al. Among authors: miller l. bioRxiv [Preprint]. 2020 Aug 3:2020.08.03.234914. doi: 10.1101/2020.08.03.234914. bioRxiv. 2020. PMID: 32793905 Free PMC article. Updated. Preprint.
Evaluating the clinical and cost-effectiveness of a conservative approach to oxygen therapy for invasively ventilated adults in intensive care: Protocol for the UK-ROX trial.
Martin DS, Shahid T, Gould DW, Richards-Belle A, Doidge JC, Camsooksai J, Charles WN, Davey M, Francis Johnson A, Garrett RM, Grocott MP, Jones J, Lampro L, Miller L, O'Driscoll BR, Rostron AJ, Sadique Z, Szakmany T, Young PJ, Rowan KM, Harrison DA, Mouncey PR. Martin DS, et al. Among authors: miller l. J Intensive Care Soc. 2024 Apr 11;25(2):223-230. doi: 10.1177/17511437241239880. eCollection 2024 May. J Intensive Care Soc. 2024. PMID: 38737312 Free PMC article.
Author's reply to Ask Not If, But Which Ablations May Be Performed In the ASC!
Liu CF, Hurwitz JL, Krahn AD, Ellenbogen KA, Slotwiner DJ, Schoenfeld MH, Pelosi F Jr, Mainigi SK, Berman AE, Rashba EJ, Hao S, Sachdev M, Larsen TR, Tsai S, Miller L, Smith AM, Shanker AJ. Liu CF, et al. Among authors: miller l. Heart Rhythm. 2024 May 6:S1547-5271(24)02544-X. doi: 10.1016/j.hrthm.2024.05.006. Online ahead of print. Heart Rhythm. 2024. PMID: 38718943 No abstract available.
7,921 results