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The Abca7V1613M variant reduces Aβ generation, plaque load, and neuronal damage.
Butler CA, Mendoza Arvilla A, Milinkeviciute G, Da Cunha C, Kawauchi S, Rezaie N, Liang HY, Javonillo D, Thach A, Wang S, Collins S, Walker A, Shi KX, Neumann J, Gomez-Arboledas A, Henningfield CM, Hohsfield LA, Mapstone M, Tenner AJ, LaFerla FM, Mortazavi A, MacGregor GR, Green KN. Butler CA, et al. Among authors: milinkeviciute g. Alzheimers Dement. 2024 Mar 20. doi: 10.1002/alz.13783. Online ahead of print. Alzheimers Dement. 2024. PMID: 38506634
BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease.
Garcia-Agudo LF, Shi Z, Smith IF, Kramár EA, Tran K, Kawauchi S, Wang S, Collins S, Walker A, Shi KX, Neumann J, Liang HY, Da Cunha C, Milinkeviciute G, Morabito S, Miyoshi E, Rezaie N, Gomez-Arboledas A, Arvilla AM, Ghaemi DI, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, Swarup V, MacGregor GR, Green KN. Garcia-Agudo LF, et al. Among authors: milinkeviciute g. Alzheimers Dement. 2024 Apr;20(4):2922-2942. doi: 10.1002/alz.13767. Epub 2024 Mar 9. Alzheimers Dement. 2024. PMID: 38460121 Free PMC article.
Genetic diversity promotes resilience in a mouse model of Alzheimer's disease.
Soni N, Hohsfield LA, Tran KM, Kawauchi S, Walker A, Javonillo D, Phan J, Matheos D, Da Cunha C, Uyar A, Milinkeviciute G, Gomez-Arboledas A, Tran K, Kaczorowski CC, Wood MA, Tenner AJ, LaFerla FM, Carter GW, Mortazavi A, Swarup V, MacGregor GR, Green KN. Soni N, et al. Among authors: milinkeviciute g. Alzheimers Dement. 2024 Apr;20(4):2794-2816. doi: 10.1002/alz.13753. Epub 2024 Mar 1. Alzheimers Dement. 2024. PMID: 38426371 Free PMC article.
Clusterin/apolipoprotein J, its isoforms and Alzheimer's disease.
Milinkeviciute G, Green KN. Milinkeviciute G, et al. Front Aging Neurosci. 2023 Apr 13;15:1167886. doi: 10.3389/fnagi.2023.1167886. eCollection 2023. Front Aging Neurosci. 2023. PMID: 37122381 Free PMC article. No abstract available.
A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques.
Tran KM, Kawauchi S, Kramár EA, Rezaie N, Liang HY, Sakr JS, Gomez-Arboledas A, Arreola MA, Cunha CD, Phan J, Wang S, Collins S, Walker A, Shi KX, Neumann J, Filimban G, Shi Z, Milinkeviciute G, Javonillo DI, Tran K, Gantuz M, Forner S, Swarup V, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, MacGregor GR, Green KN. Tran KM, et al. Among authors: milinkeviciute g. Mol Neurodegener. 2023 Feb 17;18(1):12. doi: 10.1186/s13024-023-00598-4. Mol Neurodegener. 2023. PMID: 36803190 Free PMC article.
Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease.
Javonillo DI, Tran KM, Phan J, Hingco E, Kramár EA, da Cunha C, Forner S, Kawauchi S, Milinkeviciute G, Gomez-Arboledas A, Neumann J, Banh CE, Huynh M, Matheos DP, Rezaie N, Alcantara JA, Mortazavi A, Wood MA, Tenner AJ, MacGregor GR, Green KN, LaFerla FM. Javonillo DI, et al. Among authors: milinkeviciute g. Front Neurosci. 2022 Jan 24;15:785276. doi: 10.3389/fnins.2021.785276. eCollection 2021. Front Neurosci. 2022. PMID: 35140584 Free PMC article.
Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesity.
Jayashankar V, Selwan E, Hancock SE, Verlande A, Goodson MO, Eckenstein KH, Milinkeviciute G, Hoover BM, Chen B, Fleischman AG, Cramer KS, Hanessian S, Masri S, Turner N, Edinger AL. Jayashankar V, et al. Among authors: milinkeviciute g. EMBO Mol Med. 2021 Aug 9;13(8):e13086. doi: 10.15252/emmm.202013086. Epub 2021 Jul 7. EMBO Mol Med. 2021. PMID: 34231322 Free PMC article.
16 results