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Pretreatment of Glioblastoma with Bortezomib Potentiates Natural Killer Cell Cytotoxicity through TRAIL/DR5 Mediated Apoptosis and Prolongs Animal Survival.
Gras Navarro A, Espedal H, Joseph JV, Trachsel-Moncho L, Bahador M, Gjertsen BT, Kristoffersen EK, Simonsen A, Miletic H, Enger PØ, Rahman MA, Chekenya M. Gras Navarro A, et al. Among authors: miletic h. Cancers (Basel). 2019 Jul 17;11(7):996. doi: 10.3390/cancers11070996. Cancers (Basel). 2019. PMID: 31319548 Free PMC article.
A reproducible brain tumour model established from human glioblastoma biopsies.
Wang J, Miletic H, Sakariassen PØ, Huszthy PC, Jacobsen H, Brekkå N, Li X, Zhao P, Mørk S, Chekenya M, Bjerkvig R, Enger PØ. Wang J, et al. Among authors: miletic h. BMC Cancer. 2009 Dec 29;9:465. doi: 10.1186/1471-2407-9-465. BMC Cancer. 2009. PMID: 20040089 Free PMC article.
EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis.
Talasila KM, Soentgerath A, Euskirchen P, Rosland GV, Wang J, Huszthy PC, Prestegarden L, Skaftnesmo KO, Sakariassen PØ, Eskilsson E, Stieber D, Keunen O, Brekka N, Moen I, Nigro JM, Vintermyr OK, Lund-Johansen M, Niclou S, Mørk SJ, Enger PO, Bjerkvig R, Miletic H. Talasila KM, et al. Among authors: miletic h. Acta Neuropathol. 2013 May;125(5):683-98. doi: 10.1007/s00401-013-1101-1. Epub 2013 Feb 22. Acta Neuropathol. 2013. PMID: 23429996 Free PMC article.
EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.
Eskilsson E, Rosland GV, Talasila KM, Knappskog S, Keunen O, Sottoriva A, Foerster S, Solecki G, Taxt T, Jirik R, Fritah S, Harter PN, Välk K, Al Hossain J, Joseph JV, Jahedi R, Saed HS, Piccirillo SG, Spiteri I, Leiss L, Euskirchen P, Graziani G, Daubon T, Lund-Johansen M, Enger PØ, Winkler F, Ritter CA, Niclou SP, Watts C, Bjerkvig R, Miletic H. Eskilsson E, et al. Among authors: miletic h. Neuro Oncol. 2016 Dec;18(12):1644-1655. doi: 10.1093/neuonc/now113. Epub 2016 Jun 10. Neuro Oncol. 2016. PMID: 27286795 Free PMC article.
The angiogenic switch leads to a metabolic shift in human glioblastoma.
Talasila KM, Røsland GV, Hagland HR, Eskilsson E, Flønes IH, Fritah S, Azuaje F, Atai N, Harter PN, Mittelbronn M, Andersen M, Joseph JV, Hossain JA, Vallar L, Noorden CJ, Niclou SP, Thorsen F, Tronstad KJ, Tzoulis C, Bjerkvig R, Miletic H. Talasila KM, et al. Among authors: miletic h. Neuro Oncol. 2017 Mar 1;19(3):383-393. doi: 10.1093/neuonc/now175. Neuro Oncol. 2017. PMID: 27591677 Free PMC article.
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