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The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells.
Oroń M, Grochowski M, Jaiswar A, Legierska J, Jastrzębski K, Nowak-Niezgoda M, Kołos M, Kaźmierczak W, Olesiński T, Lenarcik M, Cybulska M, Mikula M, Żylicz A, Miączyńska M, Zettl K, Wiśniewski JR, Walerych D. Oroń M, et al. Among authors: mikula m. Cell Rep. 2022 Sep 27;40(13):111428. doi: 10.1016/j.celrep.2022.111428. Cell Rep. 2022. PMID: 36170818 Free article.
Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy.
Mikula M, Skrzypczak M, Goryca K, Paczkowska K, Ledwon JK, Statkiewicz M, Kulecka M, Grzelak M, Dabrowska M, Kuklinska U, Karczmarski J, Rumienczyk I, Jastrzebski K, Miaczynska M, Ginalski K, Bomsztyk K, Ostrowski J. Mikula M, et al. Nucleic Acids Res. 2016 Dec 1;44(21):10150-10164. doi: 10.1093/nar/gkw763. Epub 2016 Sep 1. Nucleic Acids Res. 2016. PMID: 27587583 Free PMC article.
Challenges in Stratifying the Molecular Variability of Patient-Derived Colon Tumor Xenografts.
Cybulska M, Olesinski T, Goryca K, Paczkowska K, Statkiewicz M, Kopczynski M, Grochowska A, Unrug-Bielawska K, Tyl-Bielicka A, Gajewska M, Mroz A, Dabrowska M, Karczmarski J, Paziewska A, Zając L, Bednarczyk M, Mikula M, Ostrowski J. Cybulska M, et al. Among authors: mikula m. Biomed Res Int. 2018 Dec 19;2018:2954208. doi: 10.1155/2018/2954208. eCollection 2018. Biomed Res Int. 2018. PMID: 30662905 Free PMC article.
Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer.
Szymańska E, Nowak P, Kolmus K, Cybulska M, Goryca K, Derezińska-Wołek E, Szumera-Ciećkiewicz A, Brewińska-Olchowik M, Grochowska A, Piwocka K, Prochorec-Sobieszek M, Mikula M, Miączyńska M. Szymańska E, et al. Among authors: mikula m. EMBO Mol Med. 2020 Feb 7;12(2):e10812. doi: 10.15252/emmm.201910812. Epub 2020 Jan 13. EMBO Mol Med. 2020. PMID: 31930723 Free PMC article.
SYK inhibition targets acute myeloid leukemia stem cells by blocking their oxidative metabolism.
Polak A, Bialopiotrowicz E, Krzymieniewska B, Wozniak J, Stojak M, Cybulska M, Kaniuga E, Mikula M, Jablonska E, Gorniak P, Noyszewska-Kania M, Szydlowski M, Piechna K, Piwocka K, Bugajski L, Lech-Maranda E, Barankiewicz J, Kolkowska-Lesniak A, Patkowska E, Glodkowska-Mrowka E, Baran N, Juszczynski P. Polak A, et al. Among authors: mikula m. Cell Death Dis. 2020 Nov 6;11(11):956. doi: 10.1038/s41419-020-03156-8. Cell Death Dis. 2020. PMID: 33159047 Free PMC article.
ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway.
Wróbel M, Cendrowski J, Szymańska E, Grębowicz-Maciukiewicz M, Budick-Harmelin N, Macias M, Szybińska A, Mazur M, Kolmus K, Goryca K, Dąbrowska M, Paziewska A, Mikula M, Miączyńska M. Wróbel M, et al. Among authors: mikula m. Life Sci Alliance. 2022 Mar 30;5(7):e202101239. doi: 10.26508/lsa.202101239. Print 2022 Jul. Life Sci Alliance. 2022. PMID: 35354596 Free PMC article.
Correction: ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway.
Wróbel M, Cendrowski J, Szymańska E, Grębowicz-Maciukiewicz M, Budick-Harmelin N, Macias M, Szybińska A, Mazur M, Kolmus K, Goryca K, Dąbrowska M, Paziewska A, Mikula M, Miączyńska M. Wróbel M, et al. Among authors: mikula m. Life Sci Alliance. 2022 Jun 7;5(10):e202201537. doi: 10.26508/lsa.202201537. Print 2022 Oct. Life Sci Alliance. 2022. PMID: 35672146 Free PMC article. No abstract available.
219 results