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Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase.
Karabanovich G, Dušek J, Savková K, Pavliš O, Pávková I, Korábečný J, Kučera T, Kočová Vlčková H, Huszár S, Konyariková Z, Konečná K, Jand'ourek O, Stolaříková J, Korduláková J, Vávrová K, Pávek P, Klimešová V, Hrabálek A, Mikušová K, Roh J. Karabanovich G, et al. Among authors: mikusova k. J Med Chem. 2019 Sep 12;62(17):8115-8139. doi: 10.1021/acs.jmedchem.9b00912. Epub 2019 Aug 22. J Med Chem. 2019. PMID: 31393122
Synthesis, docking study and biological evaluation of ᴅ-fructofuranosyl and ᴅ-tagatofuranosyl sulfones as potential inhibitors of the mycobacterial galactan synthesis targeting the galactofuranosyltransferase GlfT2.
Baráth M, Jakubčinová J, Konyariková Z, Kozmon S, Mikušová K, Bella M. Baráth M, et al. Among authors: mikusova k. Beilstein J Org Chem. 2020 Jul 27;16:1853-1862. doi: 10.3762/bjoc.16.152. eCollection 2020. Beilstein J Org Chem. 2020. PMID: 32802202 Free PMC article.
An ABC transporter Wzm-Wzt catalyzes translocation of lipid-linked galactan across the plasma membrane in mycobacteria.
Savková K, Huszár S, Baráth P, Pakanová Z, Kozmon S, Vancová M, Tesařová M, Blaško J, Kaliňák M, Singh V, Korduláková J, Mikušová K. Savková K, et al. Among authors: mikusova k. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2023663118. doi: 10.1073/pnas.2023663118. Proc Natl Acad Sci U S A. 2021. PMID: 33879617 Free PMC article.
Side Chain-Modified Benzothiazinone Derivatives with Anti-Mycobacterial Activity.
Fan D, Wang B, Stelitano G, Savková K, Riabova O, Shi R, Wu X, Chiarelli LR, Mikušová K, Makarov V, Lu Y, Hong Y, Qiao C. Fan D, et al. Among authors: mikusova k. Biomedicines. 2023 Jul 12;11(7):1975. doi: 10.3390/biomedicines11071975. Biomedicines. 2023. PMID: 37509615 Free PMC article.
Compartmentalization of galactan biosynthesis in mycobacteria.
Savková K, Danchenko M, Fabianová V, Bellová J, Bencúrová M, Huszár S, Korduláková J, Siváková B, Baráth P, Mikušová K. Savková K, et al. Among authors: mikusova k. J Biol Chem. 2024 Mar;300(3):105768. doi: 10.1016/j.jbc.2024.105768. Epub 2024 Feb 16. J Biol Chem. 2024. PMID: 38367664 Free PMC article.
63 results