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NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility.
Kiyozumi D, Noda T, Yamaguchi R, Tobita T, Matsumura T, Shimada K, Kodani M, Kohda T, Fujihara Y, Ozawa M, Yu Z, Miklossy G, Bohren KM, Horie M, Okabe M, Matzuk MM, Ikawa M. Kiyozumi D, et al. Among authors: miklossy g. Science. 2020 Jun 5;368(6495):1132-1135. doi: 10.1126/science.aay5134. Science. 2020. PMID: 32499443 Free PMC article.
Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity.
Goebel EJ, Corpina RA, Hinck CS, Czepnik M, Castonguay R, Grenha R, Boisvert A, Miklossy G, Fullerton PT, Matzuk MM, Idone VJ, Economides AN, Kumar R, Hinck AP, Thompson TB. Goebel EJ, et al. Among authors: miklossy g. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15505-15513. doi: 10.1073/pnas.1906253116. Epub 2019 Jul 17. Proc Natl Acad Sci U S A. 2019. PMID: 31315975 Free PMC article.
Hirsutinolide Series Inhibit Stat3 Activity, Alter GCN1, MAP1B, Hsp105, G6PD, Vimentin, TrxR1, and Importin α-2 Expression, and Induce Antitumor Effects against Human Glioma.
Miklossy G, Youn UJ, Yue P, Zhang M, Chen CH, Hilliard TS, Paladino D, Li Y, Choi J, Sarkaria JN, Kawakami JK, Wongwiwatthananukit S, Chen Y, Sun D, Chang LC, Turkson J. Miklossy G, et al. J Med Chem. 2015 Oct 8;58(19):7734-48. doi: 10.1021/acs.jmedchem.5b00686. Epub 2015 Sep 17. J Med Chem. 2015. PMID: 26331426 Free PMC article.
27 results