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A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency.
Andersen OM, Bøgh N, Landau AM, Pløen GG, Jensen AMG, Monti G, Ulhøi BP, Nyengaard JR, Jacobsen KR, Jørgensen MM, Holm IE, Kristensen ML, Alstrup AKO, Hansen ESS, Teunissen CE, Breidenbach L, Droescher M, Liu Y, Pedersen HS, Callesen H, Luo Y, Bolund L, Brooks DJ, Laustsen C, Small SA, Mikkelsen LF, Sørensen CB. Andersen OM, et al. Among authors: mikkelsen lf. Cell Rep Med. 2022 Sep 20;3(9):100740. doi: 10.1016/j.xcrm.2022.100740. Epub 2022 Sep 12. Cell Rep Med. 2022. PMID: 36099918 Free PMC article.
Pre-clinical evaluation of the effect of co-medication with antibiotics and oral steroids in Göttingen Minipigs on the biological activity of the probiotic medicinal product TSO (Trichuris suis ova).
Prosberg MV, Kringel H, Kapel JS, Kapel BS, Fredensborg BL, Petersen AM, Hansen LH, Nielsen DS, Kapel HS, Jacobsen KR, Mikkelsen LF, Kapel CMO. Prosberg MV, et al. Among authors: mikkelsen lf. Parasitol Res. 2021 Feb;120(2):743-746. doi: 10.1007/s00436-020-07004-8. Epub 2021 Jan 6. Parasitol Res. 2021. PMID: 33409625
Assessing breed integrity of Göttingen Minipigs.
Reimer C, Ha NT, Sharifi AR, Geibel J, Mikkelsen LF, Schlather M, Weigend S, Simianer H. Reimer C, et al. Among authors: mikkelsen lf. BMC Genomics. 2020 Apr 16;21(1):308. doi: 10.1186/s12864-020-6590-4. BMC Genomics. 2020. PMID: 32299342 Free PMC article.
Species selection for nonclinical safety assessment of drug candidates: Examples of current industry practice.
Namdari R, Jones K, Chuang SS, Van Cruchten S, Dincer Z, Downes N, Mikkelsen LF, Harding J, Jäckel S, Jacobsen B, Kinyamu-Akunda J, Lortie A, Mhedhbi S, Mohr S, Schmitt MW, Prior H. Namdari R, et al. Among authors: mikkelsen lf. Regul Toxicol Pharmacol. 2021 Nov;126:105029. doi: 10.1016/j.yrtph.2021.105029. Epub 2021 Aug 27. Regul Toxicol Pharmacol. 2021. PMID: 34455009 Free article.
25 results