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The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex.
Papadopoulos D, Ha SA, Fleischhauer D, Uhl L, Russell TJ, Mikicic I, Schneider K, Brem A, Valanju OR, Cossa G, Gallant P, Schuelein-Voelk C, Maric HM, Beli P, Büchel G, Vos SM, Eilers M. Papadopoulos D, et al. Among authors: mikicic i. Mol Cell. 2024 Apr 26:S1097-2765(24)00285-5. doi: 10.1016/j.molcel.2024.04.007. Online ahead of print. Mol Cell. 2024. PMID: 38703770 Free article.
Axonal Lysosomal Assays for Characterizing the Effects of LRRK2 G2019S.
Bhatia P, Bickle M, Agrawal AA, Truss B, Nikolaidi A, Brockmann K, Reinhardt L, Vogel S, Szegoe EM, Pal A, Hermann A, Mikicic I, Yun M, Falkenburger B, Sterneckert J. Bhatia P, et al. Among authors: mikicic i. Biology (Basel). 2024 Jan 20;13(1):58. doi: 10.3390/biology13010058. Biology (Basel). 2024. PMID: 38275734 Free PMC article.
K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution.
Suryo Rahmanto A, Blum CJ, Scalera C, Heidelberger JB, Mesitov M, Horn-Ghetko D, Gräf JF, Mikicic I, Hobrecht R, Orekhova A, Ostermaier M, Ebersberger S, Möckel MM, Krapoth N, Da Silva Fernandes N, Mizi A, Zhu Y, Chen JX, Choudhary C, Papantonis A, Ulrich HD, Schulman BA, König J, Beli P. Suryo Rahmanto A, et al. Among authors: mikicic i. Mol Cell. 2023 Dec 7;83(23):4272-4289.e10. doi: 10.1016/j.molcel.2023.10.011. Epub 2023 Nov 10. Mol Cell. 2023. PMID: 37951215 Free article.
Nuclear myosin VI maintains replication fork stability.
Shi J, Hauschulte K, Mikicic I, Maharjan S, Arz V, Strauch T, Heidelberger JB, Schaefer JV, Dreier B, Plückthun A, Beli P, Ulrich HD, Wollscheid HP. Shi J, et al. Among authors: mikicic i. Nat Commun. 2023 Jun 24;14(1):3787. doi: 10.1038/s41467-023-39517-y. Nat Commun. 2023. PMID: 37355687 Free PMC article.
MYC multimers shield stalled replication forks from RNA polymerase.
Solvie D, Baluapuri A, Uhl L, Fleischhauer D, Endres T, Papadopoulos D, Aziba A, Gaballa A, Mikicic I, Isaakova E, Giansanti C, Jansen J, Jungblut M, Klein T, Schülein-Völk C, Maric H, Doose S, Sauer M, Beli P, Rosenwald A, Dobbelstein M, Wolf E, Eilers M. Solvie D, et al. Among authors: mikicic i. Nature. 2022 Dec;612(7938):148-155. doi: 10.1038/s41586-022-05469-4. Epub 2022 Nov 23. Nature. 2022. PMID: 36424410
PARP1 proximity proteomics reveals interaction partners at stressed replication forks.
Mosler T, Baymaz HI, Gräf JF, Mikicic I, Blattner G, Bartlett E, Ostermaier M, Piccinno R, Yang J, Voigt A, Gatti M, Pellegrino S, Altmeyer M, Luck K, Ahel I, Roukos V, Beli P. Mosler T, et al. Among authors: mikicic i. Nucleic Acids Res. 2022 Nov 11;50(20):11600-11618. doi: 10.1093/nar/gkac948. Nucleic Acids Res. 2022. PMID: 36350633 Free PMC article.