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Massively parallel enrichment of low-frequency alleles enables duplex sequencing at low depth.
Gydush G, Nguyen E, Bae JH, Blewett T, Rhoades J, Reed SC, Shea D, Xiong K, Liu R, Yu F, Leong KW, Choudhury AD, Stover DG, Tolaney SM, Krop IE, Christopher Love J, Parsons HA, Mike Makrigiorgos G, Golub TR, Adalsteinsson VA. Gydush G, et al. Among authors: mike makrigiorgos g. Nat Biomed Eng. 2022 Mar;6(3):257-266. doi: 10.1038/s41551-022-00855-9. Epub 2022 Mar 17. Nat Biomed Eng. 2022. PMID: 35301450 Free PMC article.
NRAS mutations with low allele burden have independent prognostic significance for patients with lower risk myelodysplastic syndromes.
Murphy DM, Bejar R, Stevenson K, Neuberg D, Shi Y, Cubrich C, Richardson K, Eastlake P, Garcia-Manero G, Kantarjian H, Ebert BL, Mike Makrigiorgos G. Murphy DM, et al. Among authors: mike makrigiorgos g. Leukemia. 2013 Oct;27(10):2077-81. doi: 10.1038/leu.2013.160. Epub 2013 May 27. Leukemia. 2013. PMID: 23708912 Free PMC article. No abstract available.