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Page 1
Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations.
Subramaniam A, Sandén C, Moura-Castro L, Žemaitis K, Schmiderer L, Baudet A, Bäckström A, Arvidsson E, Hultmark S, Miharada N, Magnusson M, Paulsson K, Fioretos T, Larsson J. Subramaniam A, et al. Among authors: miharada n. Haematologica. 2022 Sep 1;107(9):2271-2275. doi: 10.3324/haematol.2021.280303. Haematologica. 2022. PMID: 35638550 Free PMC article. No abstract available.
Genome-wide association study on 13 167 individuals identifies regulators of blood CD34+cell levels.
Lopez de Lapuente Portilla A, Ekdahl L, Cafaro C, Ali Z, Miharada N, Thorleifsson G, Žemaitis K, Lamarca Arrizabalaga A, Thodberg M, Pertesi M, Dhapola P, Bao E, Niroula A, Bali D, Norddahl G, Ugidos Damboriena N, Sankaran VG, Karlsson G, Thorsteinsdottir U, Larsson J, Stefansson K, Nilsson B. Lopez de Lapuente Portilla A, et al. Among authors: miharada n. Blood. 2022 Mar 17;139(11):1659-1669. doi: 10.1182/blood.2021013220. Blood. 2022. PMID: 35007327 Free article.
Ciclopirox ethanolamine preserves the immature state of human HSCs by mediating intracellular iron content.
Talkhoncheh MS, Baudet A, Ek F, Subramaniam A, Kao YR, Miharada N, Karlsson C, Oburoglu L, Rydström A, Zemaitis K, Alattar AG, Rak J, Pietras K, Olsson R, Will B, Larsson J. Talkhoncheh MS, et al. Among authors: miharada n. Blood Adv. 2023 Dec 26;7(24):7407-7417. doi: 10.1182/bloodadvances.2023009844. Blood Adv. 2023. PMID: 37487020 Free PMC article.
S100A6 is a critical regulator of hematopoietic stem cells.
Grahn THM, Niroula A, Végvári Á, Oburoglu L, Pertesi M, Warsi S, Safi F, Miharada N, Garcia SC, Siva K, Liu Y, Rörby E, Nilsson B, Zubarev RA, Karlsson S. Grahn THM, et al. Among authors: miharada n. Leukemia. 2020 Dec;34(12):3323-3337. doi: 10.1038/s41375-020-0901-2. Epub 2020 Jun 19. Leukemia. 2020. PMID: 32555370 Free PMC article.
Correction: S100A6 is a critical regulator of hematopoietic stem cells.
Grahn THM, Niroula A, Végvári Á, Oburoglu L, Pertesi M, Warsi S, Safi F, Miharada N, Capellera-Garcia S, Siva K, Liu Y, Rörby E, Nilsson B, Zubarev RA, Karlsson S. Grahn THM, et al. Among authors: miharada n. Leukemia. 2020 Dec;34(12):3439. doi: 10.1038/s41375-020-0971-1. Leukemia. 2020. PMID: 32665696 Free PMC article.
Retinoids rescue ceruloplasmin secretion and alleviate oxidative stress in Wilson's disease-specific hepatocytes.
Song D, Takahashi G, Zheng YW, Matsuo-Takasaki M, Li J, Takami M, An Y, Hemmi Y, Miharada N, Fujioka T, Noguchi M, Nakajima T, Saito MK, Nakamura Y, Oda T, Miyaoka Y, Hayashi Y. Song D, et al. Among authors: miharada n. Hum Mol Genet. 2022 Oct 28;31(21):3652-3671. doi: 10.1093/hmg/ddac080. Hum Mol Genet. 2022. PMID: 35388883 Free PMC article.