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Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen.
Miguel-Blanco C, Molina I, Bardera AI, Díaz B, de Las Heras L, Lozano S, González C, Rodrigues J, Delves MJ, Ruecker A, Colmenarejo G, Viera S, Martínez-Martínez MS, Fernández E, Baum J, Sinden RE, Herreros E. Miguel-Blanco C, et al. Nat Commun. 2017 May 17;8:15160. doi: 10.1038/ncomms15160. Nat Commun. 2017. PMID: 28513586 Free PMC article.
Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation.
Miguel-Blanco C, Lelièvre J, Delves MJ, Bardera AI, Presa JL, López-Barragán MJ, Ruecker A, Marques S, Sinden RE, Herreros E. Miguel-Blanco C, et al. Antimicrob Agents Chemother. 2015;59(6):3298-305. doi: 10.1128/AAC.04684-14. Epub 2015 Mar 23. Antimicrob Agents Chemother. 2015. PMID: 25801574 Free PMC article.
A high throughput screen for next-generation leads targeting malaria parasite transmission.
Delves MJ, Miguel-Blanco C, Matthews H, Molina I, Ruecker A, Yahiya S, Straschil U, Abraham M, León ML, Fischer OJ, Rueda-Zubiaurre A, Brandt JR, Cortés Á, Barnard A, Fuchter MJ, Calderón F, Winzeler EA, Sinden RE, Herreros E, Gamo FJ, Baum J. Delves MJ, et al. Among authors: miguel blanco c. Nat Commun. 2018 Sep 18;9(1):3805. doi: 10.1038/s41467-018-05777-2. Nat Commun. 2018. PMID: 30228275 Free PMC article.
The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957.
Miguel-Blanco C, Murithi JM, Benavente ED, Angrisano F, Sala KA, van Schalkwyk DA, Vanaerschot M, Schwach F, Fuchter MJ, Billker O, Sutherland CJ, Campino SG, Clark TG, Blagborough AM, Fidock DA, Herreros E, Gamo FJ, Baum J, Delves MJ. Miguel-Blanco C, et al. Sci Rep. 2021 Jan 21;11(1):1888. doi: 10.1038/s41598-021-81343-z. Sci Rep. 2021. PMID: 33479319 Free PMC article.
Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarials.
Tsebriy O, Khomiak A, Miguel-Blanco C, Sparkes PC, Gioli M, Santelli M, Whitley E, Gamo FJ, Delves MJ. Tsebriy O, et al. Among authors: miguel blanco c. PLoS Pathog. 2023 Oct 6;19(10):e1011711. doi: 10.1371/journal.ppat.1011711. eCollection 2023 Oct. PLoS Pathog. 2023. PMID: 37801466 Free PMC article.
Disruption of the Plasmodium falciparum Life Cycle through Transcriptional Reprogramming by Inhibitors of Jumonji Demethylases.
Matthews KA, Senagbe KM, Nötzel C, Gonzales CA, Tong X, Rijo-Ferreira F, Bhanu NV, Miguel-Blanco C, Lafuente-Monasterio MJ, Garcia BA, Kafsack BFC, Martinez ED. Matthews KA, et al. Among authors: miguel blanco c. ACS Infect Dis. 2020 May 8;6(5):1058-1075. doi: 10.1021/acsinfecdis.9b00455. Epub 2020 Apr 24. ACS Infect Dis. 2020. PMID: 32272012 Free PMC article.
The effect of biologics in lung function and quality of life of patients with united airways disease: A systematic review.
Domínguez-Ortega J, Mullol J, Álvarez Gutiérrez FJ, Miguel-Blanco C, Castillo JA, Olaguibel JM, Blanco-Aparicio M. Domínguez-Ortega J, et al. Among authors: miguel blanco c. J Allergy Clin Immunol Glob. 2023 Sep 28;3(1):100174. doi: 10.1016/j.jacig.2023.100174. eCollection 2024 Feb. J Allergy Clin Immunol Glob. 2023. PMID: 37915724 Free PMC article.
12 results