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Animal models used to assess influenza antivirals.
Mifsud EJ, Tai CM, Hurt AC. Mifsud EJ, et al. Expert Opin Drug Discov. 2018 Dec;13(12):1131-1139. doi: 10.1080/17460441.2018.1540586. Epub 2018 Oct 30. Expert Opin Drug Discov. 2018. PMID: 30362841 Review.
Baloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmission.
Lee LYY, Zhou J, Frise R, Goldhill DH, Koszalka P, Mifsud EJ, Baba K, Noda T, Ando Y, Sato K, Yuki AI, Shishido T, Uehara T, Wildum S, Zwanziger E, Collinson N, Kuhlbusch K, Clinch B, Hurt AC, Barclay WS. Lee LYY, et al. Among authors: mifsud ej. PLoS Pathog. 2020 Apr 15;16(4):e1008395. doi: 10.1371/journal.ppat.1008395. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32294137 Free PMC article.
Viral burden, inflammatory milieu and CD8+ T-cell responses to influenza virus in a second-generation thiazolide (RM-5061) and oseltamivir combination therapy study.
Nüssing S, Mifsud E, Hensen L, Koutsakos M, Wang Z, Kedzierski L, Mercuri F, Rossignol JF, Hurt AC, Kedzierska K. Nüssing S, et al. Influenza Other Respir Viruses. 2020 Nov;14(6):678-687. doi: 10.1111/irv.12776. Epub 2020 Jun 25. Influenza Other Respir Viruses. 2020. PMID: 32588557 Free PMC article.
Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model.
Lee LY, Zhou J, Koszalka P, Frise R, Farrukee R, Baba K, Miah S, Shishido T, Galiano M, Hashimoto T, Omoto S, Uehara T, Mifsud EJ, Collinson N, Kuhlbusch K, Clinch B, Wildum S, Barclay WS, Hurt AC. Lee LY, et al. Among authors: mifsud ej. PLoS Pathog. 2021 May 6;17(5):e1009527. doi: 10.1371/journal.ppat.1009527. eCollection 2021 May. PLoS Pathog. 2021. PMID: 33956888 Free PMC article.
24 results