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Towards the sustainable discovery and development of new antibiotics.
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo PB, Glaser P, Aigle B, Bode HB, Moreira R, Li Y, Luzhetskyy A, Medema MH, Pernodet JL, Stadler M, Tormo JR, Genilloud O, Truman AW, Weissman KJ, Takano E, Sabatini S, Stegmann E, Brötz-Oesterhelt H, Wohlleben W, Seemann M, Empting M, Hirsch AKH, Loretz B, Lehr CM, Titz A, Herrmann J, Jaeger T, Alt S, Hesterkamp T, Winterhalter M, Schiefer A, Pfarr K, Hoerauf A, Graz H, Graz M, Lindvall M, Ramurthy S, Karlén A, van Dongen M, Petkovic H, Keller A, Peyrane F, Donadio S, Fraisse L, Piddock LJV, Gilbert IH, Moser HE, Müller R. Miethke M, et al. Nat Rev Chem. 2021;5(10):726-749. doi: 10.1038/s41570-021-00313-1. Epub 2021 Aug 19. Nat Rev Chem. 2021. PMID: 34426795 Free PMC article. Review.
Semisynthesis and biological evaluation of amidochelocardin derivatives as broad-spectrum antibiotics.
Grandclaudon C, Birudukota NVS, Elgaher WAM, Jumde RP, Yahiaoui S, Arisetti N, Hennessen F, Hüttel S, Stadler M, Herrmann J, Miethke M, Hartmann RW, Müller R, Hirsch AKH, Brönstrup M. Grandclaudon C, et al. Among authors: miethke m. Eur J Med Chem. 2020 Feb 15;188:112005. doi: 10.1016/j.ejmech.2019.112005. Epub 2019 Dec 20. Eur J Med Chem. 2020. PMID: 31911294
Amidochelocardin Overcomes Resistance Mechanisms Exerted on Tetracyclines and Natural Chelocardin.
Hennessen F, Miethke M, Zaburannyi N, Loose M, Lukežič T, Bernecker S, Hüttel S, Jansen R, Schmiedel J, Fritzenwanker M, Imirzalioglu C, Vogel J, Westermann AJ, Hesterkamp T, Stadler M, Wagenlehner F, Petković H, Herrmann J, Müller R. Hennessen F, et al. Among authors: miethke m. Antibiotics (Basel). 2020 Sep 18;9(9):619. doi: 10.3390/antibiotics9090619. Antibiotics (Basel). 2020. PMID: 32962088 Free PMC article.
Ferri-bacillibactin uptake and hydrolysis in Bacillus subtilis.
Miethke M, Klotz O, Linne U, May JJ, Beckering CL, Marahiel MA. Miethke M, et al. Mol Microbiol. 2006 Sep;61(6):1413-27. doi: 10.1111/j.1365-2958.2006.05321.x. Epub 2006 Aug 3. Mol Microbiol. 2006. PMID: 16889643 Free article.
40 results