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Page 1
Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection.
Ullah TR, Johansen MD, Balka KR, Ambrose RL, Gearing LJ, Roest J, Vivian JP, Sapkota S, Jayasekara WSN, Wenholz DS, Aldilla VR, Zeng J, Miemczyk S, Nguyen DH, Hansbro NG, Venkatraman R, Kang JH, Pang ES, Thomas BJ, Alharbi AS, Rezwan R, O'Keeffe M, Donald WA, Ellyard JI, Wong W, Kumar N, Kile BT, Vinuesa CG, Kelly GE, Laczka OF, Hansbro PM, De Nardo D, Gantier MP. Ullah TR, et al. Among authors: miemczyk s. Nat Commun. 2023 Sep 18;14(1):5666. doi: 10.1038/s41467-023-41381-9. Nat Commun. 2023. PMID: 37723181 Free PMC article.
Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice.
Ashhurst AS, Johansen MD, Maxwell JWC, Stockdale S, Ashley CL, Aggarwal A, Siddiquee R, Miemczyk S, Nguyen DH, Mackay JP, Counoupas C, Byrne SN, Turville S, Steain M, Triccas JA, Hansbro PM, Payne RJ, Britton WJ. Ashhurst AS, et al. Among authors: miemczyk s. Nat Commun. 2022 Nov 15;13(1):6972. doi: 10.1038/s41467-022-34297-3. Nat Commun. 2022. PMID: 36379950 Free PMC article.
Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon.
Ryan TAJ, Hooftman A, Rehill AM, Johansen MD, Brien ECO, Toller-Kawahisa JE, Wilk MM, Day EA, Weiss HJ, Sarvari P, Vozza EG, Schramm F, Peace CG, Zotta A, Miemczyk S, Nalkurthi C, Hansbro NG, McManus G, O'Doherty L, Gargan S, Long A, Dunne J, Cheallaigh CN, Conlon N, Carty M, Fallon PG, Mills KHG, Creagh EM, Donnell JSO, Hertzog PJ, Hansbro PM, McLoughlin RM, Wygrecka M, Preston RJS, Zasłona Z, O'Neill LAJ. Ryan TAJ, et al. Among authors: miemczyk s. Nat Commun. 2023 Jun 14;14(1):3513. doi: 10.1038/s41467-023-39174-1. Nat Commun. 2023. PMID: 37316487 Free PMC article.
Increased SARS-CoV-2 Infection, Protease, and Inflammatory Responses in Chronic Obstructive Pulmonary Disease Primary Bronchial Epithelial Cells Defined with Single-Cell RNA Sequencing.
Johansen MD, Mahbub RM, Idrees S, Nguyen DH, Miemczyk S, Pathinayake P, Nichol K, Hansbro NG, Gearing LJ, Hertzog PJ, Gallego-Ortega D, Britton WJ, Saunders BM, Wark PA, Faiz A, Hansbro PM. Johansen MD, et al. Among authors: miemczyk s. Am J Respir Crit Care Med. 2022 Sep 15;206(6):712-729. doi: 10.1164/rccm.202108-1901OC. Am J Respir Crit Care Med. 2022. PMID: 35549656 Free PMC article.
Mucosal immunization with a delta-inulin adjuvanted recombinant spike vaccine elicits lung-resident immune memory and protects mice against SARS-CoV-2.
Stewart EL, Counoupas C, Johansen MD, Nguyen DH, Miemczyk S, Hansbro NG, Ferrell KC, Ashhurst A, Alca S, Ashley C, Steain M, Britton WJ, Hansbro PM, Petrovsky N, Triccas JA. Stewart EL, et al. Among authors: miemczyk s. Mucosal Immunol. 2022 Jun;15(6):1405-1415. doi: 10.1038/s41385-022-00578-9. Epub 2022 Nov 21. Mucosal Immunol. 2022. PMID: 36411332 Free PMC article.
Publisher Correction: Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon.
Ryan TAJ, Hooftman A, Rehill AM, Johansen MD, O' Brien EC, Toller-Kawahisa JE, Wilk MM, Day EA, Weiss HJ, Sarvari P, Vozza EG, Schramm F, Peace CG, Zotta A, Miemczyk S, Nalkurthi C, Hansbro NG, McManus G, O'Doherty L, Gargan S, Long A, Dunne J, Cheallaigh CN, Conlon N, Carty M, Fallon PG, Mills KHG, Creagh EM, O' Donnell JS, Hertzog PJ, Hansbro PM, McLoughlin RM, Wygrecka M, Preston RJS, Zasłona Z, O'Neill LAJ. Ryan TAJ, et al. Among authors: miemczyk s. Nat Commun. 2023 Jul 20;14(1):4374. doi: 10.1038/s41467-023-40034-1. Nat Commun. 2023. PMID: 37474527 Free PMC article. No abstract available.
Development of a novel angiotensin converting enzyme 2 stimulator with broad implications in SARS-CoV2 and type 1 diabetes.
Rajapakse N, Nomura H, Wu M, Song J, Hung A, Tran S, Ta H, Akther F, Wu Y, Johansen M, Chew K, Kumar V, Woodruff T, Clark R, Koehbach J, Lomonte B, Rosado C, Thomas M, Boudes M, Reboul C, Rash L, Gallo L, Essid S, Elmlund D, Miemczyk S, Hansbro N, Saunders B, Britton W, Sly P, Yamamoto A, Fernandez J, Moyle P, Short K, Hansbro P, Kuruppu S, Smith I. Rajapakse N, et al. Among authors: miemczyk s. Res Sq [Preprint]. 2023 Apr 5:rs.3.rs-2642181. doi: 10.21203/rs.3.rs-2642181/v1. Res Sq. 2023. PMID: 37066342 Free PMC article. Preprint.
GBS-MeDIP: A protocol for parallel identification of genetic and epigenetic variation in the same reduced fraction of genomes across individuals.
Rezaei S, Uffenorde J, Gimm O, Hosseinpour Feizi MA, Miemczyk S, Coutinho LL, Jensen P, Guerrero-Bosagna C, Pértille F. Rezaei S, et al. Among authors: miemczyk s. STAR Protoc. 2022 Mar 3;3(1):101202. doi: 10.1016/j.xpro.2022.101202. eCollection 2022 Mar 18. STAR Protoc. 2022. PMID: 35257114 Free PMC article.