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Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide.
Heyder NA, Kleinau G, Speck D, Schmidt A, Paisdzior S, Szczepek M, Bauer B, Koch A, Gallandi M, Kwiatkowski D, Bürger J, Mielke T, Beck-Sickinger AG, Hildebrand PW, Spahn CMT, Hilger D, Schacherl M, Biebermann H, Hilal T, Kühnen P, Kobilka BK, Scheerer P. Heyder NA, et al. Among authors: mielke t. Cell Res. 2021 Nov;31(11):1176-1189. doi: 10.1038/s41422-021-00569-8. Epub 2021 Sep 24. Cell Res. 2021. PMID: 34561620 Free PMC article.
Structure of the ribosome-bound cricket paralysis virus IRES RNA.
Schüler M, Connell SR, Lescoute A, Giesebrecht J, Dabrowski M, Schroeer B, Mielke T, Penczek PA, Westhof E, Spahn CM. Schüler M, et al. Among authors: mielke t. Nat Struct Mol Biol. 2006 Dec;13(12):1092-6. doi: 10.1038/nsmb1177. Epub 2006 Nov 19. Nat Struct Mol Biol. 2006. PMID: 17115051
A dose-rate effect in single-particle electron microscopy.
Chen JZ, Sachse C, Xu C, Mielke T, Spahn CM, Grigorieff N. Chen JZ, et al. Among authors: mielke t. J Struct Biol. 2008 Jan;161(1):92-100. doi: 10.1016/j.jsb.2007.09.017. Epub 2007 Oct 1. J Struct Biol. 2008. PMID: 17977018 Free PMC article.
GTPase activation of elongation factor EF-Tu by the ribosome during decoding.
Schuette JC, Murphy FV 4th, Kelley AC, Weir JR, Giesebrecht J, Connell SR, Loerke J, Mielke T, Zhang W, Penczek PA, Ramakrishnan V, Spahn CM. Schuette JC, et al. Among authors: mielke t. EMBO J. 2009 Mar 18;28(6):755-65. doi: 10.1038/emboj.2009.26. Epub 2009 Feb 19. EMBO J. 2009. PMID: 19229291 Free PMC article.
Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites.
Ratje AH, Loerke J, Mikolajka A, Brünner M, Hildebrand PW, Starosta AL, Dönhöfer A, Connell SR, Fucini P, Mielke T, Whitford PC, Onuchic JN, Yu Y, Sanbonmatsu KY, Hartmann RK, Penczek PA, Wilson DN, Spahn CM. Ratje AH, et al. Among authors: mielke t. Nature. 2010 Dec 2;468(7324):713-6. doi: 10.1038/nature09547. Nature. 2010. PMID: 21124459 Free PMC article.
The complex of tmRNA-SmpB and EF-G on translocating ribosomes.
Ramrath DJ, Yamamoto H, Rother K, Wittek D, Pech M, Mielke T, Loerke J, Scheerer P, Ivanov P, Teraoka Y, Shpanchenko O, Nierhaus KH, Spahn CM. Ramrath DJ, et al. Among authors: mielke t. Nature. 2012 May 6;485(7399):526-9. doi: 10.1038/nature11006. Nature. 2012. PMID: 22622583
115 results