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Interferon-Gamma-Producing CD8+ Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor-Colitis.
Sasson SC, Slevin SM, Cheung VTF, Nassiri I, Olsson-Brown A, Fryer E, Ferreira RC, Trzupek D, Gupta T, Al-Hillawi L, Issaias ML, Easton A, Campo L, FitzPatrick MEB, Adams J, Chitnis M, Protheroe A, Tuthill M, Coupe N, Simmons A, Payne M, Middleton MR, Travis SPL; Oxford Inflammatory Bowel Disease Cohort Investigators; Fairfax BP, Klenerman P, Brain O. Sasson SC, et al. Among authors: middleton mr. Gastroenterology. 2021 Oct;161(4):1229-1244.e9. doi: 10.1053/j.gastro.2021.06.025. Epub 2021 Jun 17. Gastroenterology. 2021. PMID: 34147519 Free PMC article.
Delayed oral toxicity from long-term vemurafenib therapy.
Lloyd-Lavery A, Hodgson T, Coupe N, Bond S, Shah K, Espinosa O, Payne MJ, Middleton MR, Matin RN. Lloyd-Lavery A, et al. Among authors: middleton mr. Br J Dermatol. 2016 May;174(5):1159-60. doi: 10.1111/bjd.14457. Epub 2016 Mar 30. Br J Dermatol. 2016. PMID: 26853702 No abstract available.
Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial.
Lyon PC, Gray MD, Mannaris C, Folkes LK, Stratford M, Campo L, Chung DYF, Scott S, Anderson M, Goldin R, Carlisle R, Wu F, Middleton MR, Gleeson FV, Coussios CC. Lyon PC, et al. Among authors: middleton mr. Lancet Oncol. 2018 Aug;19(8):1027-1039. doi: 10.1016/S1470-2045(18)30332-2. Epub 2018 Jul 11. Lancet Oncol. 2018. PMID: 30001990 Free PMC article. Clinical Trial.
A phase 1 study to assess the safety, tolerability, and pharmacokinetics of CXD101 in patients with advanced cancer.
Eyre TA, Collins GP, Gupta A, Coupe N, Sheikh S, Whittaker J, Wang LM, Campo L, Soilleux E, Tysoe F, Cousins R, La Thangue N, Folkes LK, Stratford MRL, Kerr D, Middleton MR. Eyre TA, et al. Among authors: middleton mr. Cancer. 2019 Jan 1;125(1):99-108. doi: 10.1002/cncr.31791. Epub 2018 Oct 17. Cancer. 2019. PMID: 30332497 Free article. Clinical Trial.
Focused Ultrasound Hyperthermia for Targeted Drug Release from Thermosensitive Liposomes: Results from a Phase I Trial.
Gray MD, Lyon PC, Mannaris C, Folkes LK, Stratford M, Campo L, Chung DYF, Scott S, Anderson M, Goldin R, Carlisle R, Wu F, Middleton MR, Gleeson FV, Coussios CC. Gray MD, et al. Among authors: middleton mr. Radiology. 2019 Apr;291(1):232-238. doi: 10.1148/radiol.2018181445. Epub 2019 Jan 15. Radiology. 2019. PMID: 30644817 Free article. Clinical Trial.
Immunotherapy-related hepatitis: real-world experience from a tertiary centre.
Cheung V, Gupta T, Payne M, Middleton MR, Collier JD, Simmons A, Klenerman P, Brain O, Cobbold JF. Cheung V, et al. Among authors: middleton mr. Frontline Gastroenterol. 2019 Oct;10(4):364-371. doi: 10.1136/flgastro-2018-101146. Epub 2019 Mar 22. Frontline Gastroenterol. 2019. PMID: 31656561 Free PMC article.
234 results