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An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid.
Perrone MG, Miciaccia M, Vitale P, Ferorelli S, Araújo CDCB, de Almeida GS, Souza Domingos TF, da Silva LCRP, de Pádula M, Cabral LM, Sathler PC, Bonaccorso C, Fortuna CG, Scilimati A. Perrone MG, et al. Among authors: miciaccia m. Eur J Med Chem. 2021 Jan 1;209:112919. doi: 10.1016/j.ejmech.2020.112919. Epub 2020 Oct 9. Eur J Med Chem. 2021. PMID: 33129592
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability.
Pati ML, Vitale P, Ferorelli S, Iaselli M, Miciaccia M, Boccarelli A, Di Mauro GD, Fortuna CG, Souza Domingos TF, Rodrigues Pereira da Silva LC, de Pádula M, Cabral LM, Sathler PC, Vacca A, Scilimati A, Perrone MG. Pati ML, et al. Among authors: miciaccia m. Eur J Med Chem. 2019 Feb 15;164:59-76. doi: 10.1016/j.ejmech.2018.12.029. Epub 2018 Dec 15. Eur J Med Chem. 2019. PMID: 30590258
Three-dimensional structure of human cyclooxygenase (hCOX)-1.
Miciaccia M, Belviso BD, Iaselli M, Cingolani G, Ferorelli S, Cappellari M, Loguercio Polosa P, Perrone MG, Caliandro R, Scilimati A. Miciaccia M, et al. Sci Rep. 2021 Feb 22;11(1):4312. doi: 10.1038/s41598-021-83438-z. Sci Rep. 2021. PMID: 33619313 Free PMC article.
Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase-1 Inhibitors by Automated De Novo Design.
Friedrich L, Cingolani G, Ko YH, Iaselli M, Miciaccia M, Perrone MG, Neukirch K, Bobinger V, Merk D, Hofstetter RK, Werz O, Koeberle A, Scilimati A, Schneider G. Friedrich L, et al. Among authors: miciaccia m. Adv Sci (Weinh). 2021 Aug;8(16):e2100832. doi: 10.1002/advs.202100832. Epub 2021 Jun 27. Adv Sci (Weinh). 2021. PMID: 34176236 Free PMC article.
Fluorochrome Selection for Imaging Intraoperative Ovarian Cancer Probes.
Perrone MG, Vitale P, Miciaccia M, Ferorelli S, Centonze A, Solidoro R, Munzone C, Bonaccorso C, Fortuna CG, Kleinmanns K, Bjørge L, Scilimati A. Perrone MG, et al. Among authors: miciaccia m. Pharmaceuticals (Basel). 2022 May 26;15(6):668. doi: 10.3390/ph15060668. Pharmaceuticals (Basel). 2022. PMID: 35745587 Free PMC article.
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