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Neoantigen-specific CD8 T cells with high structural avidity preferentially reside in and eliminate tumors.
Schmidt J, Chiffelle J, Perez MAS, Magnin M, Bobisse S, Arnaud M, Genolet R, Cesbron J, Barras D, Navarro Rodrigo B, Benedetti F, Michel A, Queiroz L, Baumgaertner P, Guillaume P, Hebeisen M, Michielin O, Nguyen-Ngoc T, Huber F, Irving M, Tissot-Renaud S, Stevenson BJ, Rusakiewicz S, Dangaj Laniti D, Bassani-Sternberg M, Rufer N, Gfeller D, Kandalaft LE, Speiser DE, Zoete V, Coukos G, Harari A. Schmidt J, et al. Among authors: michielin o. Nat Commun. 2023 Jun 6;14(1):3188. doi: 10.1038/s41467-023-38946-z. Nat Commun. 2023. PMID: 37280206 Free PMC article.
CD3 delta establishes a functional link between the T cell receptor and CD8.
Doucey MA, Goffin L, Naeher D, Michielin O, Baumgärtner P, Guillaume P, Palmer E, Luescher IF. Doucey MA, et al. Among authors: michielin o. J Biol Chem. 2003 Jan 31;278(5):3257-64. doi: 10.1074/jbc.M208119200. Epub 2002 Sep 4. J Biol Chem. 2003. PMID: 12215456 Free article.
Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma.
Romero P, Valmori D, Pittet MJ, Zippelius A, Rimoldi D, Lévy F, Dutoit V, Ayyoub M, Rubio-Godoy V, Michielin O, Guillaume P, Batard P, Luescher IF, Lejeune F, Liénard D, Rufer N, Dietrich PY, Speiser DE, Cerottini JC. Romero P, et al. Among authors: michielin o. Immunol Rev. 2002 Oct;188:81-96. doi: 10.1034/j.1600-065x.2002.18808.x. Immunol Rev. 2002. PMID: 12445283 Review.
Prevalent role of TCR alpha-chain in the selection of the preimmune repertoire specific for a human tumor-associated self-antigen.
Dietrich PY, Le Gal FA, Dutoit V, Pittet MJ, Trautman L, Zippelius A, Cognet I, Widmer V, Walker PR, Michielin O, Guillaume P, Connerotte T, Jotereau F, Coulie PG, Romero P, Cerottini JC, Bonneville M, Valmori D. Dietrich PY, et al. Among authors: michielin o. J Immunol. 2003 May 15;170(10):5103-9. doi: 10.4049/jimmunol.170.10.5103. J Immunol. 2003. PMID: 12734356
284 results