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Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
Akhlaghpour M, Haritunians T, More SK, Thomas LS, Stamps DT, Dube S, Li D, Yang S, Landers CJ, Mengesha E, Hamade H, Murali R, Potdar AA, Wolf AJ, Botwin GJ, Khrom M; International IBD Genetics Consortium; Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Sartor RB, Xavier RJ, Brant SR, Cho JH, Duerr RH, Lazarev MG, Rioux JD, Schumm LP, Silverberg MS, Zaghiyan K, Fleshner P, Melmed GY, Vasiliauskas EA, Ha C, Rabizadeh S, Syal G, Bonthala NN, Ziring DA, Targan SR, Long MD, McGovern DPB, Michelsen KS. Akhlaghpour M, et al. Among authors: michelsen ks. Gut. 2023 Nov;72(11):2068-2080. doi: 10.1136/gutjnl-2023-329689. Epub 2023 Apr 20. Gut. 2023. PMID: 37080587 Free article.
Malassezia Is Associated with Crohn's Disease and Exacerbates Colitis in Mouse Models.
Limon JJ, Tang J, Li D, Wolf AJ, Michelsen KS, Funari V, Gargus M, Nguyen C, Sharma P, Maymi VI, Iliev ID, Skalski JH, Brown J, Landers C, Borneman J, Braun J, Targan SR, McGovern DPB, Underhill DM. Limon JJ, et al. Among authors: michelsen ks. Cell Host Microbe. 2019 Mar 13;25(3):377-388.e6. doi: 10.1016/j.chom.2019.01.007. Epub 2019 Mar 5. Cell Host Microbe. 2019. PMID: 30850233 Free PMC article.
BATF3 Protects Against Metabolic Syndrome and Maintains Intestinal Epithelial Homeostasis.
Hamade H, Stamps JT, Stamps DT, More SK, Thomas LS, Blackwood AY, Lahcene NL, Castanon SL, Salumbides BC, Shimodaira Y, Goodridge HS, Targan SR, Michelsen KS. Hamade H, et al. Among authors: michelsen ks. Front Immunol. 2022 Jun 22;13:841065. doi: 10.3389/fimmu.2022.841065. eCollection 2022. Front Immunol. 2022. PMID: 35812447 Free PMC article.
DR3 Regulates Intestinal Epithelial Homeostasis and Regeneration After Intestinal Barrier Injury.
Shimodaira Y, More SK, Hamade H, Blackwood AY, Abraham JP, Thomas LS, Miller JH, Stamps DT, Castanon SL, Jacob N, Ha CWY, Devkota S, Shih DQ, Targan SR, Michelsen KS. Shimodaira Y, et al. Among authors: michelsen ks. Cell Mol Gastroenterol Hepatol. 2023;16(1):83-105. doi: 10.1016/j.jcmgh.2023.03.008. Epub 2023 Apr 1. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37011811 Free PMC article.
54 results