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Host Response Changes and Their Association with Mortality in COVID-19 Patients with Lymphopenia.
Michels EHA, Appelman B, de Brabander J, van Amstel RBE, van Linge CCA, Chouchane O, Reijnders TDY, Schuurman AR, Sulzer TAL, Klarenbeek AM, Douma RA, Bos LDJ, Wiersinga WJ, Peters-Sengers H, van der Poll T; Amsterdam UMC COVID-19 Biobank Study Group. Michels EHA, et al. Am J Respir Crit Care Med. 2024 Feb 15;209(4):402-416. doi: 10.1164/rccm.202305-0890OC. Am J Respir Crit Care Med. 2024. PMID: 37948687 Free PMC article.
Association between dexamethasone treatment and the host response in COVID-19 patients admitted to the general ward.
de Brabander J, Michels EHA, van Linge CCA, Chouchane O, Douma RA, Reijnders TDY, Schuurman AR, van Engelen TSR; Amsterdam UMC COVID-19 biobank study group; Wiersinga WJ, van der Poll T. de Brabander J, et al. Among authors: michels eha. Respir Res. 2022 Jun 3;23(1):145. doi: 10.1186/s12931-022-02060-3. Respir Res. 2022. PMID: 35659223 Free PMC article.
Age-related changes in plasma biomarkers and their association with mortality in COVID-19.
Michels EHA, Appelman B, de Brabander J, van Amstel RBE, Chouchane O, van Linge CCA, Schuurman AR, Reijnders TDY, Sulzer TAL, Klarenbeek AM, Douma RA; Amsterdam UMC COVID-19 Biobank Study Group; Bos LDJ, Wiersinga WJ, Peters-Sengers H, van der Poll T; Amsterdam UMC COVID-19 Biobank Study Group; van Agtmael M, Algera AG, Appelman B, van Baarle F, Beudel M, Bogaard HJ, Bomers M, Bonta P, Bos L, Botta M, de Brabander J, de Bree G, de Bruin S, Bugiani M, Bulle E, Buis DTP, Chouchane O, Cloherty A, Dijkstra M, Dongelmans DA, Dujardin RWG, Elbers P, Fleuren L, Geerlings S, Geijtenbeek T, Girbes A, Goorhuis B, Grobusch MP, Hagens L, Hamann J, Harris V, Hemke R, Hermans SM, Heunks L, Hollmann M, Horn J, Hovius JW, de Jong HK, de Jong MD, Koning R, Lemkes B, Lim EHT, van Mourik N, Nellen J, Nossent EJ, Olie S, Paulus F, Peters E, Pina-Fuentes DAI, van der Poll T, Preckel B, Prins JM, Raasveld J, Reijnders T, de Rotte MCFJ, Schinkel M, Schultz MJ, Schrauwen FAP, Schuurman A, Schuurmans J, Sigaloff K, Slim MA, Smeele P, Smit M, Stijnis CS, Stilma W, Teunissen C, Thoral P, Tsonas AM, Tuinman PR, van der Valk M, Veelo DP, Volleman C, de Vries H, Vught LA, van Vugt M, Wouters D, Zwinderm… See abstract for full author list ➔ Michels EHA, et al. Eur Respir J. 2023 Jul 7;62(1):2300011. doi: 10.1183/13993003.00011-2023. Print 2023 Jul. Eur Respir J. 2023. PMID: 37080568 Free PMC article.
Inflammatory and glycolytic programs underpin a primed blood neutrophil state in patients with pneumonia.
Schuurman AR, Butler JM, Michels EHA, Otto NA, Brands X, Haak BW, Uhel F, Klarenbeek AM, Faber DR, Schomakers BV, van Weeghel M, de Vos AF, Scicluna BP, Houtkooper RH, Wiersinga WJ, van der Poll T. Schuurman AR, et al. Among authors: michels eha. iScience. 2023 Jun 19;26(7):107181. doi: 10.1016/j.isci.2023.107181. eCollection 2023 Jul 21. iScience. 2023. PMID: 37496676 Free PMC article.
Thrombocytopenia is associated with a dysregulated host response in severe COVID-19.
Appelman B, Michels EHA, de Brabander J, Peters-Sengers H, van Amstel RBE, Noordzij SM, Klarenbeek AM, van Linge CCA, Chouchane O, Schuurman AR, Reijnders TDY, Douma RA, Bos LDJ; Amsterdam UMC COVID-19 Biobank study group; CovidPredict study group; Wiersinga WJ, van der Poll T. Appelman B, et al. Among authors: michels eha. Thromb Res. 2023 Sep;229:187-197. doi: 10.1016/j.thromres.2023.07.008. Epub 2023 Jul 19. Thromb Res. 2023. PMID: 37541167 Free article.
Platelets of COVID-19 patients display mitochondrial dysfunction, oxidative stress, and energy metabolism failure compatible with cell death.
Léopold V, Chouchane O, Butler JM, Schuurman AR, Michels EHA, de Brabander J, Schomakers BV, van Weeghel M, Picavet-Havik DI, Grootemaat AE, Douma RA, Reijnders TDY, Klarenbeek AM, Appelman B; Amsterdam University Medical Center COVID-19 Biobank Study Groupd.vandebeek@amsterdamumc.nl; Wiersinga WJ, van der Wel NN, den Dunnen J, Houtkooper RH, Van't Veer C, van der Poll T; Amsterdam University Medical Center COVID-19 Biobank Study Group. Léopold V, et al. Among authors: michels eha. Res Pract Thromb Haemost. 2023 Sep 28;7(7):102213. doi: 10.1016/j.rpth.2023.102213. eCollection 2023 Oct. Res Pract Thromb Haemost. 2023. PMID: 38077825 Free PMC article.
Kaliuresis and Intracellular Uptake of Potassium with Potassium Citrate and Potassium Chloride Supplements: A Randomized Controlled Trial.
Wouda RD, Gritter M, Karsten M, Michels EHA, Nieuweboer TM, Danser AHJ, de Borst MH, Hoorn EJ, Rotmans JI, Vogt L. Wouda RD, et al. Among authors: michels eha. Clin J Am Soc Nephrol. 2023 Oct 1;18(10):1260-1271. doi: 10.2215/CJN.0000000000000228. Epub 2023 Jun 29. Clin J Am Soc Nephrol. 2023. PMID: 37382933 Clinical Trial.