Michelet R - Search Results

1

Nonlinear Mixed-Effects Model of Z-Endoxifen Concentrations in Tamoxifen-Treated Patients from the CEPAM Cohort.

Mc Laughlin AM, Helland T, Klima F, Koolen SLW, van Schaik RHN, Mathijssen RHJ, Neven P, Swen JJ, Guchelaar HJ, Dalenc F, White-Koning M, Michelet R, Mikus G, Schroth W, Mürdter T, Brauch H, Schwab M, Søiland H, Mellgren G, Thomas F, Kloft C, Hertz DL; CYP2D6 Endoxifen Percentage Activity Model (CEPAM) Consortium. Mc Laughlin AM, et al. Among authors: michelet r. Clin Pharmacol Ther. 2024 Mar 18. doi: 10.1002/cpt.3238. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 38494911

2

Obesity Alters Endoxifen Plasma Levels in Young Breast Cancer Patients: A Pharmacometric Simulation Approach.

Mueller-Schoell A, Klopp-Schulze L, Schroth W, Mürdter T, Michelet R, Brauch H, Huisinga W, Joerger M, Neven P, Koolen SLW, Mathijssen RHJ, Copson E, Eccles D, Chen S, Chowbay B, Tfayli A, Zgheib NK, Schwab M, Kloft C. Mueller-Schoell A, et al. Among authors: michelet r. Clin Pharmacol Ther. 2020 Sep;108(3):661-670. doi: 10.1002/cpt.1960. Epub 2020 Jul 23. Clin Pharmacol Ther. 2020. PMID: 32578187

3

Simulation-Based Assessment of the Impact of Non-Adherence on Endoxifen Target Attainment in Different Tamoxifen Dosing Strategies.

Mueller-Schoell A, Klopp-Schulze L, Michelet R, van Dyk M, Mürdter TE, Schwab M, Joerger M, Huisinga W, Mikus G, Kloft C. Mueller-Schoell A, et al. Among authors: michelet r. Pharmaceuticals (Basel). 2021 Feb 3;14(2):115. doi: 10.3390/ph14020115. Pharmaceuticals (Basel). 2021. PMID: 33546125 Free PMC article.

4

Towards Model-Informed Precision Dosing of Voriconazole: Challenging Published Voriconazole Nonlinear Mixed-Effects Models with Real-World Clinical Data.

Kluwe F, Michelet R, Huisinga W, Zeitlinger M, Mikus G, Kloft C. Kluwe F, et al. Among authors: michelet r. Clin Pharmacokinet. 2023 Oct;62(10):1461-1477. doi: 10.1007/s40262-023-01274-y. Epub 2023 Aug 21. Clin Pharmacokinet. 2023. PMID: 37603216 Free PMC article.

5

Computational Treatment Simulations to Assess the Need for Personalized Tamoxifen Dosing in Breast Cancer Patients of Different Biogeographical Groups.

Mueller-Schoell A, Michelet R, Klopp-Schulze L, van Dyk M, Mürdter TE, Schwab M, Joerger M, Huisinga W, Mikus G, Kloft C. Mueller-Schoell A, et al. Among authors: michelet r. Cancers (Basel). 2021 May 18;13(10):2432. doi: 10.3390/cancers13102432. Cancers (Basel). 2021. PMID: 34069810 Free PMC article.

6

Perspectives on Model-Informed Precision Dosing in the Digital Health Era: Challenges, Opportunities, and Recommendations.

Kluwe F, Michelet R, Mueller-Schoell A, Maier C, Klopp-Schulze L, van Dyk M, Mikus G, Huisinga W, Kloft C. Kluwe F, et al. Among authors: michelet r. Clin Pharmacol Ther. 2021 Jan;109(1):29-36. doi: 10.1002/cpt.2049. Epub 2020 Oct 17. Clin Pharmacol Ther. 2021. PMID: 33068303 No abstract available.

7

CYP2D6 phenotype explains reported yohimbine concentrations in four severe acute intoxications.

Mueller-Schoell A, Michelet R, Weinelt F, Kloft C, Mikus G. Mueller-Schoell A, et al. Among authors: michelet r. Arch Toxicol. 2021 Aug;95(8):2867-2870. doi: 10.1007/s00204-021-03082-4. Epub 2021 May 24. Arch Toxicol. 2021. PMID: 34027562 Free PMC article.

8

Novel insights into the complex pharmacokinetics of voriconazole: a review of its metabolism.

Schulz J, Kluwe F, Mikus G, Michelet R, Kloft C. Schulz J, et al. Among authors: michelet r. Drug Metab Rev. 2019 Aug;51(3):247-265. doi: 10.1080/03602532.2019.1632888. Epub 2019 Aug 16. Drug Metab Rev. 2019. PMID: 31215810 Review.

9

Towards the Elucidation of the Pharmacokinetics of Voriconazole: A Quantitative Characterization of Its Metabolism.

Schulz J, Thomas A, Saleh A, Mikus G, Kloft C, Michelet R. Schulz J, et al. Among authors: michelet r. Pharmaceutics. 2022 Feb 22;14(3):477. doi: 10.3390/pharmaceutics14030477. Pharmaceutics. 2022. PMID: 35335853 Free PMC article.

10

Microdialysis of Drug and Drug Metabolite: a Comprehensive In Vitro Analysis for Voriconazole and Voriconazole N-oxide.

Schulz J, Michelet R, Zeitlinger M, Mikus G, Kloft C. Schulz J, et al. Among authors: michelet r. Pharm Res. 2022 Nov;39(11):2991-3003. doi: 10.1007/s11095-022-03292-0. Epub 2022 Sep 28. Pharm Res. 2022. PMID: 36171344 Free PMC article.

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