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LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus.
Wu Z, Berlemann LA, Bader V, Sehr DA, Dawin E, Covallero A, Meschede J, Angersbach L, Showkat C, Michaelis JB, Münch C, Rieger B, Namgaladze D, Herrera MG, Fiesel FC, Springer W, Mendes M, Stepien J, Barkovits K, Marcus K, Sickmann A, Dittmar G, Busch KB, Riedel D, Brini M, Tatzelt J, Cali T, Winklhofer KF. Wu Z, et al. Among authors: michaelis jb. EMBO J. 2022 Dec 15;41(24):e112006. doi: 10.15252/embj.2022112006. Epub 2022 Nov 18. EMBO J. 2022. PMID: 36398858 Free PMC article.
Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury.
Poluzzi C, Nastase MV, Zeng-Brouwers J, Roedig H, Hsieh LT, Michaelis JB, Buhl EM, Rezende F, Manavski Y, Bleich A, Boor P, Brandes RP, Pfeilschifter J, Stelzer EHK, Münch C, Dikic I, Brandts C, Iozzo RV, Wygrecka M, Schaefer L. Poluzzi C, et al. Among authors: michaelis jb. Kidney Int. 2019 Mar;95(3):540-562. doi: 10.1016/j.kint.2018.10.037. Epub 2019 Jan 31. Kidney Int. 2019. PMID: 30712922 Free article.
Mitochondria shed their outer membrane in response to infection-induced stress.
Li X, Straub J, Medeiros TC, Mehra C, den Brave F, Peker E, Atanassov I, Stillger K, Michaelis JB, Burbridge E, Adrain C, Münch C, Riemer J, Becker T, Pernas LF. Li X, et al. Among authors: michaelis jb. Science. 2022 Jan 14;375(6577):eabi4343. doi: 10.1126/science.abi4343. Epub 2022 Jan 14. Science. 2022. PMID: 35025629
A20 binding and inhibitor of nuclear factor kappa B (NF-κB)-1 (ABIN-1): a novel modulator of mitochondrial autophagy.
Merline R, Rödig H, Zeng-Brouwers J, Poluzzi C, Tascher G, Michaelis J, Lopez-Mosqueda J, Rhiner A, Huber LS, Diehl V, Dikic I, Kögel D, Münch C, Wygrecka M, Schaefer L. Merline R, et al. Am J Physiol Cell Physiol. 2023 Feb 1;324(2):C339-C352. doi: 10.1152/ajpcell.00493.2022. Epub 2022 Nov 28. Am J Physiol Cell Physiol. 2023. PMID: 36440857 Free PMC article.
A Eukaryotic Sensor for Membrane Lipid Saturation.
Covino R, Ballweg S, Stordeur C, Michaelis JB, Puth K, Wernig F, Bahrami A, Ernst AM, Hummer G, Ernst R. Covino R, et al. Among authors: michaelis jb. Mol Cell. 2016 Jul 7;63(1):49-59. doi: 10.1016/j.molcel.2016.05.015. Epub 2016 Jun 16. Mol Cell. 2016. PMID: 27320200 Free article.