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Clostridial C3 Toxins Enter and Intoxicate Human Dendritic Cells.
Fellermann M, Huchler C, Fechter L, Kolb T, Wondany F, Mayer D, Michaelis J, Stenger S, Mellert K, Möller P, Barth TFE, Fischer S, Barth H. Fellermann M, et al. Among authors: michaelis j. Toxins (Basel). 2020 Sep 1;12(9):563. doi: 10.3390/toxins12090563. Toxins (Basel). 2020. PMID: 32883045 Free PMC article.
Cyclophilin-facilitated membrane translocation as pharmacological target to prevent intoxication of mammalian cells by binary clostridial actin ADP-ribosylated toxins.
Ernst K, Langer S, Kaiser E, Osseforth C, Michaelis J, Popoff MR, Schwan C, Aktories K, Kahlert V, Malesevic M, Schiene-Fischer C, Barth H. Ernst K, et al. Among authors: michaelis j. J Mol Biol. 2015 Mar 27;427(6 Pt A):1224-38. doi: 10.1016/j.jmb.2014.07.013. Epub 2014 Jul 21. J Mol Biol. 2015. PMID: 25058685 Free article.
Super-resolution microscopy unveils transmembrane domain-mediated internalization of cross-reacting material 197 into diphtheria toxin-resistant mouse J774A.1 cells and primary rat fibroblasts in vitro.
Fellermann M, Wondany F, Carle S, Nemeth J, Sadhanasatish T, Frick M, Barth H, Michaelis J. Fellermann M, et al. Among authors: michaelis j. Arch Toxicol. 2020 May;94(5):1753-1761. doi: 10.1007/s00204-020-02731-4. Epub 2020 Apr 8. Arch Toxicol. 2020. PMID: 32266418 Free PMC article.
The enzyme subunit SubA of Shiga toxin-producing E. coli strains demonstrates comparable intracellular transport and cytotoxic activity as the holotoxin SubAB in HeLa and HCT116 cells in vitro.
Sessler K, Papatheodorou P, Wondany F, Krause M, Noettger S, Bernhard D, Michaelis J, Schmidt H, Barth H. Sessler K, et al. Among authors: michaelis j. Arch Toxicol. 2021 Mar;95(3):975-983. doi: 10.1007/s00204-020-02965-2. Epub 2021 Jan 23. Arch Toxicol. 2021. PMID: 33483759 Free PMC article.
Delivery by Dendritic Mesoporous Silica Nanoparticles Enhances the Antimicrobial Activity of a Napsin-Derived Peptide Against Intracellular Mycobacterium tuberculosis.
Beitzinger B, Gerbl F, Vomhof T, Schmid R, Noschka R, Rodriguez A, Wiese S, Weidinger G, Ständker L, Walther P, Michaelis J, Lindén M, Stenger S. Beitzinger B, et al. Among authors: michaelis j. Adv Healthc Mater. 2021 Jul;10(14):e2100453. doi: 10.1002/adhm.202100453. Epub 2021 Jun 17. Adv Healthc Mater. 2021. PMID: 34142469
277 results