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Using histopathology latent diffusion models as privacy-preserving dataset augmenters improves downstream classification performance.
Niehues JM, Müller-Franzes G, Schirris Y, Wagner SJ, Jendrusch M, Kloor M, Pearson AT, Muti HS, Hewitt KJ, Veldhuizen GP, Zigutyte L, Truhn D, Kather JN. Niehues JM, et al. Among authors: jendrusch m. Comput Biol Med. 2024 Apr 4;175:108410. doi: 10.1016/j.compbiomed.2024.108410. Online ahead of print. Comput Biol Med. 2024. PMID: 38678938
A simple approach for detecting HLA-A*02 alleles in archival formalin-fixed paraffin-embedded tissue samples and an application example for studying cancer immunoediting.
Witt J, Haupt S, Ahadova A, Bohaumilitzky L, Fuchs V, Ballhausen A, Przybilla MJ, Jendrusch M, Seppälä TT, Fürst D, Walle T, Busch E, Haag GM, Hüneburg R, Nattermann J, von Knebel Doeberitz M, Heuveline V, Kloor M. Witt J, et al. Among authors: jendrusch m. HLA. 2023 Jan;101(1):24-33. doi: 10.1111/tan.14846. Epub 2022 Oct 25. HLA. 2023. PMID: 36251018
Deep learning detects genetic alterations in cancer histology generated by adversarial networks.
Krause J, Grabsch HI, Kloor M, Jendrusch M, Echle A, Buelow RD, Boor P, Luedde T, Brinker TJ, Trautwein C, Pearson AT, Quirke P, Jenniskens J, Offermans K, van den Brandt PA, Kather JN. Krause J, et al. Among authors: jendrusch m. J Pathol. 2021 May;254(1):70-79. doi: 10.1002/path.5638. Epub 2021 Mar 16. J Pathol. 2021. PMID: 33565124 Free article.
The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution.
Ballhausen A, Przybilla MJ, Jendrusch M, Haupt S, Pfaffendorf E, Seidler F, Witt J, Hernandez Sanchez A, Urban K, Draxlbauer M, Krausert S, Ahadova A, Kalteis MS, Pfuderer PL, Heid D, Stichel D, Gebert J, Bonsack M, Schott S, Bläker H, Seppälä T, Mecklin JP, Ten Broeke S, Nielsen M, Heuveline V, Krzykalla J, Benner A, Riemer AB, von Knebel Doeberitz M, Kloor M. Ballhausen A, et al. Among authors: jendrusch m. Nat Commun. 2020 Sep 21;11(1):4740. doi: 10.1038/s41467-020-18514-5. Nat Commun. 2020. PMID: 32958755 Free PMC article.