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The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells.
Oroń M, Grochowski M, Jaiswar A, Legierska J, Jastrzębski K, Nowak-Niezgoda M, Kołos M, Kaźmierczak W, Olesiński T, Lenarcik M, Cybulska M, Mikula M, Żylicz A, Miączyńska M, Zettl K, Wiśniewski JR, Walerych D. Oroń M, et al. Among authors: miaczynska m. Cell Rep. 2022 Sep 27;40(13):111428. doi: 10.1016/j.celrep.2022.111428. Cell Rep. 2022. PMID: 36170818 Free article.
Dynamin inhibitors impair endocytosis and mitogenic signaling of PDGF.
Sadowski Ł, Jastrzębski K, Kalaidzidis Y, Heldin CH, Hellberg C, Miaczynska M. Sadowski Ł, et al. Among authors: miaczynska m. Traffic. 2013 Jun;14(6):725-36. doi: 10.1111/tra.12061. Epub 2013 Mar 12. Traffic. 2013. PMID: 23425318 Free PMC article.
Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling.
Toruń A, Szymańska E, Castanon I, Wolińska-Nizioł L, Bartosik A, Jastrzębski K, Miętkowska M, González-Gaitán M, Miaczynska M. Toruń A, et al. Among authors: miaczynska m. PLoS One. 2015 Jun 25;10(6):e0130818. doi: 10.1371/journal.pone.0130818. eCollection 2015. PLoS One. 2015. PMID: 26110841 Free PMC article.
ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors.
Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M. Mamińska A, et al. Among authors: miaczynska m. Sci Signal. 2016 Jan 19;9(411):ra8. doi: 10.1126/scisignal.aad0848. Sci Signal. 2016. PMID: 26787452
Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy.
Mikula M, Skrzypczak M, Goryca K, Paczkowska K, Ledwon JK, Statkiewicz M, Kulecka M, Grzelak M, Dabrowska M, Kuklinska U, Karczmarski J, Rumienczyk I, Jastrzebski K, Miaczynska M, Ginalski K, Bomsztyk K, Ostrowski J. Mikula M, et al. Among authors: miaczynska m. Nucleic Acids Res. 2016 Dec 1;44(21):10150-10164. doi: 10.1093/nar/gkw763. Epub 2016 Sep 1. Nucleic Acids Res. 2016. PMID: 27587583 Free PMC article.
Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer.
Szymańska E, Nowak P, Kolmus K, Cybulska M, Goryca K, Derezińska-Wołek E, Szumera-Ciećkiewicz A, Brewińska-Olchowik M, Grochowska A, Piwocka K, Prochorec-Sobieszek M, Mikula M, Miączyńska M. Szymańska E, et al. Among authors: miaczynska m. EMBO Mol Med. 2020 Feb 7;12(2):e10812. doi: 10.15252/emmm.201910812. Epub 2020 Jan 13. EMBO Mol Med. 2020. PMID: 31930723 Free PMC article.
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