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Pharmacological inhibition of bromodomain and extra-terminal proteins induces an NRF-2-mediated antiviral state that is subverted by SARS-CoV-2 infection.
Mhlekude B, Postmus D, Stenzel S, Weiner J 3rd, Jansen J, Zapatero-Belinchón FJ, Olmer R, Richter A, Heinze J, Heinemann N, Mühlemann B, Schroeder S, Jones TC, Müller MA, Drosten C, Pich A, Thiel V, Martin U, Niemeyer D, Gerold G, Beule D, Goffinet C. Mhlekude B, et al. PLoS Pathog. 2023 Sep 25;19(9):e1011657. doi: 10.1371/journal.ppat.1011657. eCollection 2023 Sep. PLoS Pathog. 2023. PMID: 37747932 Free PMC article.
90K/LGALS3BP expression is upregulated in COVID-19 but may not restrict SARS-CoV-2 infection.
Bosquillon de Jarcy L, Akbil B, Mhlekude B, Leyens J, Postmus D, Harnisch G, Jansen J, Schmidt ML, Aigner A, Pott F, Chua RL, Krist L, Gentile R, Mühlemann B, Jones TC, Niemeyer D, Fricke J, Keil T, Pischon T, Janke J, Conrad C, Iacobelli S, Drosten C, Corman VM, Ralser M, Eils R, Kurth F, Sander L, Goffinet C. Bosquillon de Jarcy L, et al. Among authors: mhlekude b. Clin Exp Med. 2023 Nov;23(7):3689-3700. doi: 10.1007/s10238-023-01077-2. Epub 2023 May 10. Clin Exp Med. 2023. PMID: 37162650 Free PMC article.
A realistic transfer method reveals low risk of SARS-CoV-2 transmission via contaminated euro coins and banknotes.
Todt D, Meister TL, Tamele B, Howes J, Paulmann D, Becker B, Brill FH, Wind M, Schijven J, Heinen N, Kinast V, Mhlekude B, Goffinet C, Krawczyk A, Steinmann J, Pfaender S, Brüggemann Y, Steinmann E. Todt D, et al. Among authors: mhlekude b. iScience. 2021 Aug 20;24(8):102908. doi: 10.1016/j.isci.2021.102908. Epub 2021 Jul 26. iScience. 2021. PMID: 34337354 Free PMC article.