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An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers.
Mezheyeuski A, Backman M, Mattsson J, Martín-Bernabé A, Larsson C, Hrynchyk I, Hammarström K, Ström S, Ekström J, Mauchanski S, Khelashvili S, Lindberg A, Agnarsdóttir M, Edqvist PH, Huvila J, Segersten U, Malmström PU, Botling J, Nodin B, Hedner C, Borg D, Brändstedt J, Sartor H, Leandersson K, Glimelius B, Portyanko A, Ponten F, Jirström K, Micke P, Sjöblom T. Mezheyeuski A, et al. EBioMedicine. 2023 Feb;88:104452. doi: 10.1016/j.ebiom.2023.104452. Epub 2023 Jan 30. EBioMedicine. 2023. PMID: 36724681 Free PMC article.
STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer.
Peña C, Céspedes MV, Lindh MB, Kiflemariam S, Mezheyeuski A, Edqvist PH, Hägglöf C, Birgisson H, Bojmar L, Jirström K, Sandström P, Olsson E, Veerla S, Gallardo A, Sjöblom T, Chang AC, Reddel RR, Mangues R, Augsten M, Ostman A. Peña C, et al. Among authors: mezheyeuski a. Cancer Res. 2013 Feb 15;73(4):1287-97. doi: 10.1158/0008-5472.CAN-12-1875. Epub 2012 Dec 14. Cancer Res. 2013. PMID: 23243022
Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer.
Mezheyeuski A, Bradic Lindh M, Guren TK, Dragomir A, Pfeiffer P, Kure EH, Ikdahl T, Skovlund E, Corvigno S, Strell C, Pietras K, Ponten F, Mulder J, Qvortrup C, Portyanko A, Tveit KM, Glimelius B, Sorbye H, Östman A. Mezheyeuski A, et al. Oncotarget. 2016 Jul 5;7(27):41948-41958. doi: 10.18632/oncotarget.9632. Oncotarget. 2016. PMID: 27248825 Free PMC article. Clinical Trial.
Multi-parametric profiling of renal cell, colorectal, and ovarian cancer identifies tumour-type-specific stroma phenotypes and a novel vascular biomarker.
Corvigno S, Frödin M, Wisman GBA, Nijman HW, Van der Zee AG, Jirström K, Nodin B, Hrynchyk I, Edler D, Ragnhammar P, Johansson M, Dahlstrand H, Mezheyeuski A, Östman A. Corvigno S, et al. Among authors: mezheyeuski a. J Pathol Clin Res. 2017 Jul 24;3(3):214-224. doi: 10.1002/cjp2.74. eCollection 2017 Jul. J Pathol Clin Res. 2017. PMID: 28770105 Free PMC article.
Treatment-related survival associations of claudin-2 expression in fibroblasts of colorectal cancer.
Mezheyeuski A, Strell C, Hrynchyk I, Guren TK, Dragomir A, Doroshenko T, Pashkova O, Gorgun J, Ruksha K, Pfeiffer P, Kure EH, Sorbye H, Edler D, Martling A, Glimelius B, Östman A, Portyanko A. Mezheyeuski A, et al. Virchows Arch. 2018 Mar;472(3):395-405. doi: 10.1007/s00428-017-2263-3. Epub 2017 Nov 13. Virchows Arch. 2018. PMID: 29134439 Free PMC article.
62 results