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Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3.
Szpakowska M, Nevins AM, Meyrath M, Rhainds D, D'huys T, Guité-Vinet F, Dupuis N, Gauthier PA, Counson M, Kleist A, St-Onge G, Hanson J, Schols D, Volkman BF, Heveker N, Chevigné A. Szpakowska M, et al. Among authors: meyrath m. Br J Pharmacol. 2018 May;175(9):1419-1438. doi: 10.1111/bph.14132. Epub 2018 Mar 23. Br J Pharmacol. 2018. PMID: 29272550 Free PMC article.
CXCL14 Preferentially Synergizes With Homeostatic Chemokine Receptor Systems.
Kouzeli A, Collins PJ, Metzemaekers M, Meyrath M, Szpakowska M, Artinger M, Struyf S, Proost P, Chevigne A, Legler DF, Eberl M, Moser B. Kouzeli A, et al. Among authors: meyrath m. Front Immunol. 2020 Oct 5;11:561404. doi: 10.3389/fimmu.2020.561404. eCollection 2020. Front Immunol. 2020. PMID: 33123134 Free PMC article.
Mutational analysis of the extracellular disulphide bridges of the atypical chemokine receptor ACKR3/CXCR7 uncovers multiple binding and activation modes for its chemokine and endogenous non-chemokine agonists.
Szpakowska M, Meyrath M, Reynders N, Counson M, Hanson J, Steyaert J, Chevigné A. Szpakowska M, et al. Among authors: meyrath m. Biochem Pharmacol. 2018 Jul;153:299-309. doi: 10.1016/j.bcp.2018.03.007. Epub 2018 Mar 9. Biochem Pharmacol. 2018. PMID: 29530506
CXCL10 Is an Agonist of the CC Family Chemokine Scavenger Receptor ACKR2/D6.
Chevigné A, Janji B, Meyrath M, Reynders N, D'Uonnolo G, Uchański T, Xiao M, Berchem G, Ollert M, Kwon YJ, Noman MZ, Szpakowska M. Chevigné A, et al. Among authors: meyrath m. Cancers (Basel). 2021 Mar 2;13(5):1054. doi: 10.3390/cancers13051054. Cancers (Basel). 2021. PMID: 33801414 Free PMC article.
24 results