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Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders.
Pavlou M, Schön C, Occelli LM, Rossi A, Meumann N, Boyd RF, Bartoe JT, Siedlecki J, Gerhardt MJ, Babutzka S, Bogedein J, Wagner JE, Priglinger SG, Biel M, Petersen-Jones SM, Büning H, Michalakis S. Pavlou M, et al. Among authors: meumann n. EMBO Mol Med. 2021 Apr 9;13(4):e13392. doi: 10.15252/emmm.202013392. Epub 2021 Feb 22. EMBO Mol Med. 2021. PMID: 33616280 Free PMC article.
Engineering the AAV capsid to optimize vector-host-interactions.
Büning H, Huber A, Zhang L, Meumann N, Hacker U. Büning H, et al. Among authors: meumann n. Curr Opin Pharmacol. 2015 Oct;24:94-104. doi: 10.1016/j.coph.2015.08.002. Epub 2015 Aug 25. Curr Opin Pharmacol. 2015. PMID: 26302254 Review.
Hepatocellular Carcinoma Is a Natural Target for Adeno-Associated Virus (AAV) 2 Vectors.
Meumann N, Schmithals C, Elenschneider L, Hansen T, Balakrishnan A, Hu Q, Hook S, Schmitz J, Bräsen JH, Franke AC, Olarewaju O, Brandenberger C, Talbot SR, Fangmann J, Hacker UT, Odenthal M, Ott M, Piiper A, Büning H. Meumann N, et al. Cancers (Basel). 2022 Jan 15;14(2):427. doi: 10.3390/cancers14020427. Cancers (Basel). 2022. PMID: 35053588 Free PMC article.
Adeno-associated virus serotype 2 capsid variants for improved liver-directed gene therapy.
Meumann N, Cabanes-Creus M, Ertelt M, Navarro RG, Lucifora J, Yuan Q, Nien-Huber K, Abdelrahman A, Vu XK, Zhang L, Franke AC, Schmithals C, Piiper A, Vogt A, Gonzalez-Carmona M, Frueh JT, Ullrich E, Meuleman P, Talbot SR, Odenthal M, Ott M, Seifried E, Schoeder CT, Schwäble J, Lisowski L, Büning H. Meumann N, et al. Hepatology. 2023 Mar 1;77(3):802-815. doi: 10.1002/hep.32733. Epub 2023 Feb 17. Hepatology. 2023. PMID: 35976053 Free PMC article.
A multiplexed barcode approach to simultaneously evaluate gene delivery by adeno-associated virus capsid variants in nonhuman primates.
Stone D, Meumann N, Kuhlmann AS, Peterson CW, Xie H, Roychoudhury P, Loprieno MA, Vu XK, Strongin DE, Kenkel EJ, Haick A, Stensland L, Obenza WM, Parrott J, Nelson V, Murnane RD, Huang ML, Aubert M, Kiem HP, Büning H, Jerome KR. Stone D, et al. Among authors: meumann n. Hepatol Commun. 2023 Jan 20;7(2):e0009. doi: 10.1097/HC9.0000000000000009. eCollection 2023 Feb 1. Hepatol Commun. 2023. PMID: 37074875 Free PMC article.
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