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Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium.
Deprez J, Verbeke R, Meulewaeter S, Aernout I, Dewitte H, Decruy T, Coudenys J, Van Duyse J, Van Isterdael G, Peer D, van der Meel R, De Smedt SC, Jacques P, Elewaut D, Lentacker I. Deprez J, et al. Among authors: meulewaeter s. Nat Nanotechnol. 2023 Nov;18(11):1341-1350. doi: 10.1038/s41565-023-01444-w. Epub 2023 Jul 10. Nat Nanotechnol. 2023. PMID: 37430039
Alpha-galactosylceramide improves the potency of mRNA LNP vaccines against cancer and intracellular bacteria.
Meulewaeter S, Aernout I, Deprez J, Engelen Y, De Velder M, Franceschini L, Breckpot K, Van Calenbergh S, Asselman C, Boucher K, Impens F, De Smedt SC, Verbeke R, Lentacker I. Meulewaeter S, et al. J Control Release. 2024 May 4;370:379-391. doi: 10.1016/j.jconrel.2024.04.052. Online ahead of print. J Control Release. 2024. PMID: 38697317 Free article.
Considerations on the Design of Lipid-based mRNA Vaccines Against Cancer.
Meulewaeter S, Zhang Y, Wadhwa A, Fox K, Lentacker I, Harder KW, Cullis PR, De Smedt SC, Cheng MHY, Verbeke R. Meulewaeter S, et al. J Mol Biol. 2024 Jan 15;436(2):168385. doi: 10.1016/j.jmb.2023.168385. Epub 2023 Dec 6. J Mol Biol. 2024. PMID: 38065276 Review.
Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine.
Ertveldt T, Meulewaeter S, De Vlaeminck Y, Olarte O, Broos K, Van Calenbergh S, Bourgeois S, Deprez J, Heremans Y, Goyvaerts C, Staels W, De Smedt S, Dewitte H, Devoogdt N, Keyaerts M, Verbeke R, Barbé K, Lentacker I, Breckpot K. Ertveldt T, et al. Among authors: meulewaeter s. Theranostics. 2023 Oct 9;13(15):5483-5500. doi: 10.7150/thno.85106. eCollection 2023. Theranostics. 2023. PMID: 37908728 Free PMC article.