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148 results

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Dual PI3K/mTOR inhibition shows antileukemic activity in MLL-rearranged acute myeloid leukemia.
Sandhöfer N, Metzeler KH, Rothenberg M, Herold T, Tiedt S, Groiß V, Carlet M, Walter G, Hinrichsen T, Wachter O, Grunert M, Schneider S, Subklewe M, Dufour A, Fröhling S, Klein HG, Hiddemann W, Jeremias I, Spiekermann K. Sandhöfer N, et al. Among authors: metzeler kh. Leukemia. 2015 Apr;29(4):828-38. doi: 10.1038/leu.2014.305. Epub 2014 Oct 17. Leukemia. 2015. PMID: 25322685
[Fortuitous finding: thrombocytopenia and thrombocytosis].
Metzeler KH, Braess J, Spiekermann K, Bohlander SK, Hiddemann W, Buske C, Feuring-Buske M. Metzeler KH, et al. MMW Fortschr Med. 2007 Apr 12;149(15):34-5, 37. MMW Fortschr Med. 2007. PMID: 17668774 German.
Stem cell gene expression programs influence clinical outcome in human leukemia.
Eppert K, Takenaka K, Lechman ER, Waldron L, Nilsson B, van Galen P, Metzeler KH, Poeppl A, Ling V, Beyene J, Canty AJ, Danska JS, Bohlander SK, Buske C, Minden MD, Golub TR, Jurisica I, Ebert BL, Dick JE. Eppert K, et al. Among authors: metzeler kh. Nat Med. 2011 Aug 28;17(9):1086-93. doi: 10.1038/nm.2415. Nat Med. 2011. PMID: 21873988
Genome-wide methylation profiling in decitabine-treated patients with acute myeloid leukemia.
Yan P, Frankhouser D, Murphy M, Tam HH, Rodriguez B, Curfman J, Trimarchi M, Geyer S, Wu YZ, Whitman SP, Metzeler K, Walker A, Klisovic R, Jacob S, Grever MR, Byrd JC, Bloomfield CD, Garzon R, Blum W, Caligiuri MA, Bundschuh R, Marcucci G. Yan P, et al. Blood. 2012 Sep 20;120(12):2466-74. doi: 10.1182/blood-2012-05-429175. Epub 2012 Jul 11. Blood. 2012. PMID: 22786882 Free PMC article.
GAS6 expression identifies high-risk adult AML patients: potential implications for therapy.
Whitman SP, Kohlschmidt J, Maharry K, Volinia S, Mrózek K, Nicolet D, Schwind S, Becker H, Metzeler KH, Mendler JH, Eisfeld AK, Carroll AJ, Powell BL, Carter TH, Baer MR, Kolitz JE, Park IK, Stone RM, Caligiuri MA, Marcucci G, Bloomfield CD. Whitman SP, et al. Among authors: metzeler kh. Leukemia. 2014 Jun;28(6):1252-1258. doi: 10.1038/leu.2013.371. Epub 2013 Dec 11. Leukemia. 2014. PMID: 24326683 Free PMC article.
An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia.
Herold T, Jurinovic V, Metzeler KH, Boulesteix AL, Bergmann M, Seiler T, Mulaw M, Thoene S, Dufour A, Pasalic Z, Schmidberger M, Schmidt M, Schneider S, Kakadia PM, Feuring-Buske M, Braess J, Spiekermann K, Mansmann U, Hiddemann W, Buske C, Bohlander SK. Herold T, et al. Among authors: metzeler kh. Leukemia. 2011 Oct;25(10):1639-45. doi: 10.1038/leu.2011.125. Epub 2011 May 31. Leukemia. 2011. PMID: 21625232 No abstract available.
Relapse of acute myeloid leukemia after allogeneic stem cell transplantation is associated with gain of WT1 alterations and high mutation load.
Vosberg S, Hartmann L, Metzeler KH, Konstandin NP, Schneider S, Varadharajan A, Hauser A, Krebs S, Blum H, Bohlander SK, Hiddemann W, Tischer J, Spiekermann K, Greif PA. Vosberg S, et al. Among authors: metzeler kh. Haematologica. 2018 Dec;103(12):e581-e584. doi: 10.3324/haematol.2018.193102. Epub 2018 Jun 28. Haematologica. 2018. PMID: 29954937 Free PMC article. No abstract available.
148 results