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Page 1
HERVs characterize normal and leukemia stem cells and represent a source of shared epitopes for cancer immunotherapy.
Alcazer V, Bonaventura P, Tonon L, Michel E, Mutez V, Fabres C, Chuvin N, Boulos R, Estornes Y, Maguer-Satta V, Geistlich K, Viari A, Metzeler KH, Hiddemann W, Batch AMN, Herold T, Caux C, Depil S. Alcazer V, et al. Among authors: metzeler kh. Am J Hematol. 2022 Sep;97(9):1200-1214. doi: 10.1002/ajh.26647. Epub 2022 Jul 12. Am J Hematol. 2022. PMID: 35759575 Free PMC article.
[Diagnostics and therapy of acute myeloid leukemia].
Fritsch S, Metzeler K, Hiddemann W, Buske C. Fritsch S, et al. Dtsch Med Wochenschr. 2006 Oct 27;131(43):2401-6. doi: 10.1055/s-2006-955022. Dtsch Med Wochenschr. 2006. PMID: 17054056 Review. German. No abstract available.
An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia.
Metzeler KH, Hummel M, Bloomfield CD, Spiekermann K, Braess J, Sauerland MC, Heinecke A, Radmacher M, Marcucci G, Whitman SP, Maharry K, Paschka P, Larson RA, Berdel WE, Büchner T, Wörmann B, Mansmann U, Hiddemann W, Bohlander SK, Buske C; Cancer and Leukemia Group B; German AML Cooperative Group. Metzeler KH, et al. Blood. 2008 Nov 15;112(10):4193-201. doi: 10.1182/blood-2008-02-134411. Epub 2008 Aug 20. Blood. 2008. PMID: 18716133 Free PMC article. Clinical Trial.
Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome.
Dufour A, Schneider F, Metzeler KH, Hoster E, Schneider S, Zellmeier E, Benthaus T, Sauerland MC, Berdel WE, Büchner T, Wörmann B, Braess J, Hiddemann W, Bohlander SK, Spiekermann K. Dufour A, et al. Among authors: metzeler kh. J Clin Oncol. 2010 Feb 1;28(4):570-7. doi: 10.1200/JCO.2008.21.6010. Epub 2009 Dec 28. J Clin Oncol. 2010. PMID: 20038735
RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes.
Greif PA, Konstandin NP, Metzeler KH, Herold T, Pasalic Z, Ksienzyk B, Dufour A, Schneider F, Schneider S, Kakadia PM, Braess J, Sauerland MC, Berdel WE, Büchner T, Woermann BJ, Hiddemann W, Spiekermann K, Bohlander SK. Greif PA, et al. Among authors: metzeler kh. Haematologica. 2012 Dec;97(12):1909-15. doi: 10.3324/haematol.2012.064667. Epub 2012 Jun 11. Haematologica. 2012. PMID: 22689681 Free PMC article.
High expression of lymphoid enhancer-binding factor-1 (LEF1) is a novel favorable prognostic factor in cytogenetically normal acute myeloid leukemia.
Metzeler KH, Heilmeier B, Edmaier KE, Rawat VP, Dufour A, Döhner K, Feuring-Buske M, Braess J, Spiekermann K, Büchner T, Sauerland MC, Döhner H, Hiddemann W, Bohlander SK, Schlenk RF, Bullinger L, Buske C. Metzeler KH, et al. Blood. 2012 Sep 6;120(10):2118-26. doi: 10.1182/blood-2012-02-411827. Epub 2012 Jul 18. Blood. 2012. PMID: 22815426 Free article.
High expression of MZB1 predicts adverse prognosis in chronic lymphocytic leukemia, follicular lymphoma and diffuse large B-cell lymphoma and is associated with a unique gene expression signature.
Herold T, Mulaw MA, Jurinovic V, Seiler T, Metzeler KH, Dufour A, Schneider S, Kakadia PM, Spiekermann K, Mansmann U, Hiddemann W, Buske C, Dreyling M, Bohlander SK. Herold T, et al. Among authors: metzeler kh. Leuk Lymphoma. 2013 Aug;54(8):1652-7. doi: 10.3109/10428194.2012.753445. Epub 2012 Dec 27. Leuk Lymphoma. 2013. PMID: 23189934
147 results