Metzakopian E - Search Results

1

HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion.

Lin JQ, Khuperkar D, Pavlou S, Makarchuk S, Patikas N, Lee FC, Zbiegly JM, Kang J, Field SF, Bailey DM, Freeman JL, Ule J, Metzakopian E, Ruepp MD, Mallucci GR. Lin JQ, et al. Among authors: metzakopian e. EMBO J. 2023 Jul 17;42(14):e113168. doi: 10.15252/embj.2022113168. Epub 2023 May 30. EMBO J. 2023. PMID: 37248947 Free PMC article.

2

Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages.

Stott SR, Metzakopian E, Lin W, Kaestner KH, Hen R, Ang SL. Stott SR, et al. Among authors: metzakopian e. J Neurosci. 2013 May 1;33(18):8022-34. doi: 10.1523/JNEUROSCI.4774-12.2013. J Neurosci. 2013. PMID: 23637192 Free PMC article.

3

A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer.

Rad R, Rad L, Wang W, Strong A, Ponstingl H, Bronner IF, Mayho M, Steiger K, Weber J, Hieber M, Veltkamp C, Eser S, Geumann U, Öllinger R, Zukowska M, Barenboim M, Maresch R, Cadiñanos J, Friedrich M, Varela I, Constantino-Casas F, Sarver A, Ten Hoeve J, Prosser H, Seidler B, Bauer J, Heikenwälder M, Metzakopian E, Krug A, Ehmer U, Schneider G, Knösel T, Rümmele P, Aust D, Grützmann R, Pilarsky C, Ning Z, Wessels L, Schmid RM, Quail MA, Vassiliou G, Esposito I, Liu P, Saur D, Bradley A. Rad R, et al. Among authors: metzakopian e. Nat Genet. 2015 Jan;47(1):47-56. doi: 10.1038/ng.3164. Epub 2014 Dec 8. Nat Genet. 2015. PMID: 25485836

4

Enhancing the genome editing toolbox: genome wide CRISPR arrayed libraries.

Metzakopian E, Strong A, Iyer V, Hodgkins A, Tzelepis K, Antunes L, Friedrich MJ, Kang Q, Davidson T, Lamberth J, Hoffmann C, Davis GD, Vassiliou GS, Skarnes WC, Bradley A. Metzakopian E, et al. Sci Rep. 2017 May 22;7(1):2244. doi: 10.1038/s41598-017-01766-5. Sci Rep. 2017. PMID: 28533524 Free PMC article.

5

Single-Cell Transcriptomics of Parkinson's Disease Human In Vitro Models Reveals Dopamine Neuron-Specific Stress Responses.

Fernandes HJR, Patikas N, Foskolou S, Field SF, Park JE, Byrne ML, Bassett AR, Metzakopian E. Fernandes HJR, et al. Among authors: metzakopian e. Cell Rep. 2020 Oct 13;33(2):108263. doi: 10.1016/j.celrep.2020.108263. Cell Rep. 2020. PMID: 33053338 Free article.

6

Development and Application of High-Throughput Single Cell Lipid Profiling: A Study of SNCA-A53T Human Dopamine Neurons.

Snowden SG, Fernandes HJR, Kent J, Foskolou S, Tate P, Field SF, Metzakopian E, Koulman A. Snowden SG, et al. Among authors: metzakopian e. iScience. 2020 Oct 21;23(11):101703. doi: 10.1016/j.isci.2020.101703. eCollection 2020 Nov 20. iScience. 2020. PMID: 33196026 Free PMC article.

7

The transcription factor BCL11A defines distinct subsets of midbrain dopaminergic neurons.

Tolve M, Ulusoy A, Patikas N, Islam KUS, Bodea GO, Öztürk E, Broske B, Mentani A, Wagener A, van Loo KMJ, Britsch S, Liu P, Khaled WT, Metzakopian E, Baader SL, Di Monte DA, Blaess S. Tolve M, et al. Among authors: metzakopian e. Cell Rep. 2021 Sep 14;36(11):109697. doi: 10.1016/j.celrep.2021.109697. Cell Rep. 2021. PMID: 34525371 Free article.

8

Derivation of nociceptive sensory neurons from hiPSCs with early patterning and temporally controlled NEUROG2 overexpression.

Plumbly W, Patikas N, Field SF, Foskolou S, Metzakopian E. Plumbly W, et al. Among authors: metzakopian e. Cell Rep Methods. 2022 Nov 15;2(11):100341. doi: 10.1016/j.crmeth.2022.100341. eCollection 2022 Nov 21. Cell Rep Methods. 2022. PMID: 36452863 Free PMC article.

9

CRISPR-Cas9 genetic screen leads to the discovery of L-Moses, a KAT2B inhibitor that attenuates Tunicamycin-mediated neuronal cell death.

Pavlou S, Foskolou S, Patikas N, Field SF, Papachristou EK, Santos C, Edwards AR, Kishore K, Ansari R, Rajan SS, Fernandes HJR, Metzakopian E. Pavlou S, et al. Among authors: metzakopian e. Sci Rep. 2023 Mar 9;13(1):3934. doi: 10.1038/s41598-023-31141-6. Sci Rep. 2023. PMID: 36894612 Free PMC article.

10

Single-cell transcriptomics identifies perturbed molecular pathways in midbrain organoids using α-synuclein triplication Parkinson's disease patient-derived iPSCs.

Patikas N, Ansari R, Metzakopian E. Patikas N, et al. Among authors: metzakopian e. Neurosci Res. 2023 Oct;195:13-28. doi: 10.1016/j.neures.2023.06.001. Epub 2023 Jun 3. Neurosci Res. 2023. PMID: 37271312 Free article.

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