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Ligand efficiency indices as guideposts for drug discovery.
Abad-Zapatero C, Metz JT. Abad-Zapatero C, et al. Among authors: metz jt. Drug Discov Today. 2005 Apr 1;10(7):464-9. doi: 10.1016/S1359-6446(05)03386-6. Drug Discov Today. 2005. PMID: 15809192 No abstract available.
Navigating the kinome.
Metz JT, Johnson EF, Soni NB, Merta PJ, Kifle L, Hajduk PJ. Metz JT, et al. Nat Chem Biol. 2011 Apr;7(4):200-2. doi: 10.1038/nchembio.530. Epub 2011 Feb 20. Nat Chem Biol. 2011. PMID: 21336281
Non-amidine-containing 1,2-dibenzamidobenzene inhibitors of human factor Xa with potent anticoagulant and antithrombotic activity.
Masters JJ, Franciskovich JB, Tinsley JM, Campbell C, Campbell JB, Craft TJ, Froelich LL, Gifford-Moore DS, Hay LA, Herron DK, Klimkowski VJ, Kurz KD, Metz JT, Ratz AM, Shuman RT, Smith GF, Smith T, Towner RD, Wiley MR, Wilson A, Yee YK. Masters JJ, et al. Among authors: metz jt. J Med Chem. 2000 Jun 1;43(11):2087-92. doi: 10.1021/jm990625b. J Med Chem. 2000. PMID: 10841787 No abstract available.
16 results