Metsä-Ketelä M - Search Results

1

Co-factor independent oxidases ncnN and actVA-3 are involved in the dimerization of benzoisochromanequinone antibiotics in naphthocyclinone and actinorhodin biosynthesis.

Baral B, Matroodi S, Siitonen V, Thapa K, Akhgari A, Yamada K, Nuutila A, Metsä-Ketelä M. Baral B, et al. Among authors: metsa ketela m. FEMS Microbiol Lett. 2023 Jan 17;370:fnad123. doi: 10.1093/femsle/fnad123. FEMS Microbiol Lett. 2023. PMID: 37989784 Free PMC article.

2

Identification of late-stage glycosylation steps in the biosynthetic pathway of the anthracycline nogalamycin.

Siitonen V, Claesson M, Patrikainen P, Aromaa M, Mäntsälä P, Schneider G, Metsä-Ketelä M. Siitonen V, et al. Chembiochem. 2012 Jan 2;13(1):120-8. doi: 10.1002/cbic.201100637. Epub 2011 Nov 25. Chembiochem. 2012. PMID: 22120896

3

Discovery of a two-component monooxygenase SnoaW/SnoaL2 involved in nogalamycin biosynthesis.

Siitonen V, Blauenburg B, Kallio P, Mäntsälä P, Metsä-Ketelä M. Siitonen V, et al. Chem Biol. 2012 May 25;19(5):638-46. doi: 10.1016/j.chembiol.2012.04.009. Chem Biol. 2012. PMID: 22633415

4

Molecular evolution of the bacterial pseudouridine-5'-phosphate glycosidase protein family.

Thapa K, Oja T, Metsä-Ketelä M. Thapa K, et al. FEBS J. 2014 Oct;281(19):4439-49. doi: 10.1111/febs.12950. Epub 2014 Aug 25. FEBS J. 2014. PMID: 25081867 Free article.

5

Structure-based engineering of angucyclinone 6-ketoreductases.

Patrikainen P, Niiranen L, Thapa K, Paananen P, Tähtinen P, Mäntsälä P, Niemi J, Metsä-Ketelä M. Patrikainen P, et al. Chem Biol. 2014 Oct 23;21(10):1381-1391. doi: 10.1016/j.chembiol.2014.07.017. Epub 2014 Sep 4. Chem Biol. 2014. PMID: 25200607

6

Divergent non-heme iron enzymes in the nogalamycin biosynthetic pathway.

Siitonen V, Selvaraj B, Niiranen L, Lindqvist Y, Schneider G, Metsä-Ketelä M. Siitonen V, et al. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5251-6. doi: 10.1073/pnas.1525034113. Epub 2016 Apr 25. Proc Natl Acad Sci U S A. 2016. PMID: 27114534 Free PMC article.

7

Laboratory course on Streptomyces genetics and secondary metabolism.

Siitonen V, Räty K, Metsä-Ketelä M. Siitonen V, et al. Biochem Mol Biol Educ. 2016 Sep 10;44(5):492-9. doi: 10.1002/bmb.20970. Epub 2016 May 18. Biochem Mol Biol Educ. 2016. PMID: 27192442 Free article.

8

Discovery of the Showdomycin Gene Cluster from Streptomyces showdoensis ATCC 15227 Yields Insight into the Biosynthetic Logic of C-Nucleoside Antibiotics.

Palmu K, Rosenqvist P, Thapa K, Ilina Y, Siitonen V, Baral B, Mäkinen J, Belogurov G, Virta P, Niemi J, Metsä-Ketelä M. Palmu K, et al. ACS Chem Biol. 2017 Jun 16;12(6):1472-1477. doi: 10.1021/acschembio.7b00078. Epub 2017 Apr 27. ACS Chem Biol. 2017. PMID: 28418235 Free article.

9

Enzymatic Synthesis of the C-Glycosidic Moiety of Nogalamycin R.

Siitonen V, Nji Wandi B, Törmänen AP, Metsä-Ketelä M. Siitonen V, et al. ACS Chem Biol. 2018 Sep 21;13(9):2433-2437. doi: 10.1021/acschembio.8b00658. Epub 2018 Aug 20. ACS Chem Biol. 2018. PMID: 30114358 Free PMC article.

10

Activation of microbial secondary metabolic pathways: Avenues and challenges.

Baral B, Akhgari A, Metsä-Ketelä M. Baral B, et al. Synth Syst Biotechnol. 2018 Sep 12;3(3):163-178. doi: 10.1016/j.synbio.2018.09.001. eCollection 2018 Sep. Synth Syst Biotechnol. 2018. PMID: 30345402 Free PMC article. Review.

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