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Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.
Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, Jekabsons MB, Jonas EA, Jordán J, Lipton SA, Manfredi G, Mattson MP, McLaughlin B, Methner A, Murphy AN, Murphy MP, Nicholls DG, Polster BM, Pozzan T, Rizzuto R, Satrústegui J, Slack RS, Swanson RA, Swerdlow RH, Will Y, Ying Z, Joselin A, Gioran A, Moreira Pinho C, Watters O, Salvucci M, Llorente-Folch I, Park DS, Bano D, Ankarcrona M, Pizzo P, Prehn JHM. Connolly NMC, et al. Among authors: methner a. Cell Death Differ. 2018 Mar;25(3):542-572. doi: 10.1038/s41418-017-0020-4. Epub 2017 Dec 11. Cell Death Differ. 2018. PMID: 29229998 Free PMC article. Review.
Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease.
Arnoux I, Willam M, Griesche N, Krummeich J, Watari H, Offermann N, Weber S, Narayan Dey P, Chen C, Monteiro O, Buettner S, Meyer K, Bano D, Radyushkin K, Langston R, Lambert JJ, Wanker E, Methner A, Krauss S, Schweiger S, Stroh A. Arnoux I, et al. Among authors: methner a. Elife. 2018 Sep 4;7:e38744. doi: 10.7554/eLife.38744. Elife. 2018. PMID: 30179155 Free PMC article.
BAX inhibitor-1 is a Ca(2+) channel critically important for immune cell function and survival.
Lisak D, Schacht T, Gawlitza A, Albrecht P, Aktas O, Koop B, Gliem M, Hofstetter HH, Zanger K, Bultynck G, Parys JB, De Smedt H, Kindler T, Adams-Quack P, Hahn M, Waisman A, Reed JC, Hövelmeyer N, Methner A. Lisak D, et al. Among authors: methner a. Cell Death Differ. 2016 Feb;23(2):358-68. doi: 10.1038/cdd.2015.115. Epub 2015 Oct 16. Cell Death Differ. 2016. PMID: 26470731 Free PMC article.
Phosphoinositide 3-kinases upregulate system xc(-) via eukaryotic initiation factor 2α and activating transcription factor 4 - A pathway active in glioblastomas and epilepsy.
Lewerenz J, Baxter P, Kassubek R, Albrecht P, Van Liefferinge J, Westhoff MA, Halatsch ME, Karpel-Massler G, Meakin PJ, Hayes JD, Aronica E, Smolders I, Ludolph AC, Methner A, Conrad M, Massie A, Hardingham GE, Maher P. Lewerenz J, et al. Among authors: methner a. Antioxid Redox Signal. 2014 Jun 20;20(18):2907-22. doi: 10.1089/ars.2013.5455. Epub 2014 Feb 6. Antioxid Redox Signal. 2014. PMID: 24219064 Free PMC article.
Charcot-Marie-Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential.
Noack R, Frede S, Albrecht P, Henke N, Pfeiffer A, Knoll K, Dehmel T, Meyer Zu Hörste G, Stettner M, Kieseier BC, Summer H, Golz S, Kochanski A, Wiedau-Pazos M, Arnold S, Lewerenz J, Methner A. Noack R, et al. Among authors: methner a. Hum Mol Genet. 2012 Jan 1;21(1):150-62. doi: 10.1093/hmg/ddr450. Epub 2011 Sep 28. Hum Mol Genet. 2012. PMID: 21965300
Regulators of mitochondrial Ca(2+) homeostasis in cerebral ischemia.
Schäfer MK, Pfeiffer A, Jaeckel M, Pouya A, Dolga AM, Methner A. Schäfer MK, et al. Among authors: methner a. Cell Tissue Res. 2014 Aug;357(2):395-405. doi: 10.1007/s00441-014-1807-y. Epub 2014 Apr 9. Cell Tissue Res. 2014. PMID: 24715113 Review.
102 results