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Allogeneic Anti-BCMA CAR T Cells Are Superior to Multiple Myeloma-derived CAR T Cells in Preclinical Studies and May Be Combined with Gamma Secretase Inhibitors.
Metelo AM, Jozwik A, Luong LA, Dominey-Foy D, Graham C, Attwood C, Inam S, Dunlop A, Sanchez K, Cuthill K, Rice C, Streetly M, Bentley T, Boldajipour B, Sommer C, Sasu B, Benjamin R. Metelo AM, et al. Cancer Res Commun. 2022 Mar 23;2(3):158-171. doi: 10.1158/2767-9764.CRC-21-0157. eCollection 2022 Mar. Cancer Res Commun. 2022. PMID: 36874402 Free PMC article.
Gene-edited healthy donor CAR T cells show superior anti-tumour activity compared to CAR T cells derived from patients with lymphoma in an in vivo model of high-grade lymphoma.
Graham CE, Jozwik A, Quartey-Papafio R, Ioannou N, Metelo AM, Scala C, Dickson G, Stewart O, Almena-Carrasco M, Peranzoni E, Ramsay AG, Patten PEM, Pertel T, Farzaneh F, Dupouy S, Pepper A, Benjamin R. Graham CE, et al. Among authors: metelo am. Leukemia. 2021 Dec;35(12):3581-3584. doi: 10.1038/s41375-021-01324-z. Epub 2021 Jun 18. Leukemia. 2021. PMID: 34145373 Free PMC article. No abstract available.
Nitrogen Trapping as a Therapeutic Strategy in Tumors with Mitochondrial Dysfunction.
Madala HR, Helenius IT, Zhou W, Mills E, Zhang Y, Liu Y, Metelo AM, Kelley ML, Punganuru S, Kim KB, Olenchock B, Rhee E, Intlekofer AM, Iliopoulos O, Chouchani E, Yeh JJ. Madala HR, et al. Among authors: metelo am. Cancer Res. 2020 Sep 1;80(17):3492-3506. doi: 10.1158/0008-5472.CAN-20-0246. Epub 2020 Jul 10. Cancer Res. 2020. PMID: 32651261 Free PMC article.
HIF2a inhibitors for the treatment of VHL disease.
Metelo AM, Noonan H, Iliopoulos O. Metelo AM, et al. Oncotarget. 2015 Sep 15;6(27):23036-7. doi: 10.18632/oncotarget.4564. Oncotarget. 2015. PMID: 26325097 Free PMC article. Review. No abstract available.
Study of the antidiabetic capacity of the VO(dmpp)2 complex.
Passadouro M, Metelo AM, Melão AS, Pedro JR, Faneca H, Carvalho E, Castro MM. Passadouro M, et al. Among authors: metelo am. J Inorg Biochem. 2010 Sep;104(9):987-92. doi: 10.1016/j.jinorgbio.2010.05.004. Epub 2010 May 15. J Inorg Biochem. 2010. PMID: 20627316